Great Humby is a hamlet in the South Kesteven district of Lincolnshire, England. It lies in the civil parish of Ropsley and Humby, 6 miles (9.7 km) east from Grantham, 1.5 miles (2.4 km) south-east from Ropsley and 3 miles (4.8 km) south from the A52. Little Humby, a larger hamlet, is 720 yards (658.4 m) to the north. It is in the civil parish of Ropsley and Humby.