The George R. Minot House is a National Historic Landmark in Brookline, Massachusetts. It is an architecturally undistinguished vernacular Colonial Revival brick house, probably built in the 1920s. The 2+1⁄2-story main block has an attached 1+1⁄2-story ell, and two end chimneys. The hip roof is pierced by gabled dormers, and a pedimented portico shelters the front entry.