Carlyle Harris (September 1868 – May 8, 1893) was a medical student who was convicted and sentenced to death for the murder of his wife. A student at New York College of Physicians and Surgeons, Harris murdered his wife, Mary Helen Potts, whom he had married on February 8, 1890, with an overdose of morphine in the form of sleeping pills. Although Potts' death was first attributed to a stroke, the murder was discovered by physicians only because she displayed severely contracted pupils, a characteristic symptom of morphine poisoning.