William Hoffman Keister (August 17, 1871 – August 19, 1924) was a professional baseball player who played infielder and outfielder in the Major Leagues from 1896 to 1903. He would play for the Baltimore Orioles (NL), Boston Beaneaters, St. Louis Cardinals, Baltimore Orioles (AL), Washington Senators, and Philadelphia Phillies. In the five full seasons that he played, each of the teams that Keister played for finished last in the league for double plays.