The proper development of the atrioventricular canal into its prospective components (The heart septum and associated valves) to create a clear division between the four compartments of the heart and ensure proper blood movement through the heart, are essential for proper heart function. When this process does not happen correctly, a child will develop atrioventricular canal defect which occurs in 2 out of every 10,000 births. It also has a correlation with Down syndrome because 20% of children with Down syndrome have atrioventricular canal disease as well. This is a very serious condition and surgery is necessary within the first six months of life for a child. Half of the children who are untreated with this condition die during their first year due to heart failure or pneumonia.
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| - Atrioventricular canal (en)
- Canal atrioventricular (pt)
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| - O defeito do canal átrio-ventricular é uma malformação congênita complexa, na qual intervêm a parte baixa do septo inter-atrial, as válvulas mitral e tricúspide e a parte alta do septo inter-ventricular. As válvulas mitral e tricúspide são substituídas por uma única válvula. É uma anomalia do desenvolvimento embrionário a nível da "crux cordis" (zona de interseção do sulco átrio-ventricular com o plano dos septos inter-auricular e inter-ventricular). (pt)
- The proper development of the atrioventricular canal into its prospective components (The heart septum and associated valves) to create a clear division between the four compartments of the heart and ensure proper blood movement through the heart, are essential for proper heart function. When this process does not happen correctly, a child will develop atrioventricular canal defect which occurs in 2 out of every 10,000 births. It also has a correlation with Down syndrome because 20% of children with Down syndrome have atrioventricular canal disease as well. This is a very serious condition and surgery is necessary within the first six months of life for a child. Half of the children who are untreated with this condition die during their first year due to heart failure or pneumonia. (en)
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| - Atrioventricular canal (en)
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| - Atrioventricular canal (en)
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| - The proper development of the atrioventricular canal into its prospective components (The heart septum and associated valves) to create a clear division between the four compartments of the heart and ensure proper blood movement through the heart, are essential for proper heart function. When this process does not happen correctly, a child will develop atrioventricular canal defect which occurs in 2 out of every 10,000 births. It also has a correlation with Down syndrome because 20% of children with Down syndrome have atrioventricular canal disease as well. This is a very serious condition and surgery is necessary within the first six months of life for a child. Half of the children who are untreated with this condition die during their first year due to heart failure or pneumonia. Atrioventricular canal defect is a combination of abnormalities of the heart and is present at birth. There is a problem when there are holes present in the walls that separate chambers (septa), as well as when valves are incorrectly constructed.There are other names for these heart abnormalities such as endocardial cushion defects or atrioventricular septal defect (en)
- O defeito do canal átrio-ventricular é uma malformação congênita complexa, na qual intervêm a parte baixa do septo inter-atrial, as válvulas mitral e tricúspide e a parte alta do septo inter-ventricular. As válvulas mitral e tricúspide são substituídas por uma única válvula. É uma anomalia do desenvolvimento embrionário a nível da "crux cordis" (zona de interseção do sulco átrio-ventricular com o plano dos septos inter-auricular e inter-ventricular). (pt)
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