Andrew DeLuca, M.D. is a fictional character from the medical drama television series Grey's Anatomy, which airs on ABC in the United States. The character was portrayed by Giacomo Gianniotti. Gianniotti was cast in April 2015 and was promoted to series regular status in January 2016. In 2018, Gianniotti reprised his role in the spin-off series Station 19 as a guest. Gianniotti exited the series in the seventeenth season. For his performance, Gianniotti was nominated for two Golden Maple Awards in 2016.