The 2022 MLS Next Pro season is the inaugural season of MLS Next Pro, the reserve league of Major League Soccer. It is the first season since 2014 where MLS had a standalone reserve league, the previous season being the MLS Reserve League. Including both MLS Next Pro and the MLS Reserve League, it is the ninth season of a reserve league operated by MLS. The league is sanctioned as a third division league by U.S. Soccer. Columbus Crew 2 defeated St. Louis City SC 2 4-1 in the inaugural MLS Next Pro Cup final on October 8.