The 2020-21 Creighton Bluejays men's basketball team represented Creighton University in the 2020-21 NCAA Division I men's basketball season. The Bluejays were led by 11th-year head coach Greg McDermott and played their home games at the CHI Health Center Omaha in Omaha, Nebraska, as members of the Big East Conference. They finished the season 22–9, 14–6 to finish second in Big East play. They defeated Butler and UConn in the Big East tournament before losing to Georgetown in the championship game. They received an at-large bid to the NCAA tournament as the No. 5 seed in the West region. They defeated UC Santa Barbara and Ohio to advance to the Sweet Sixteen. This marked the first time Creighton had won consecutive games in the same tournament and the first time they had advanced to the Sw