The 2011 Southern Miss Golden Eagles football team represented the University of Southern Mississippi in the 2011 NCAA Division I FBS football season. The Golden Eagles were led by fourth-year head coach Larry Fedora and played their home games at M. M. Roberts Stadium. They are a member of the East Division of Conference USA. They finished the season 12–2, 7–2 in C-USA play. They were champions of the East Division and defeated undefeated Houston, 49–28, in the C-USA Championship Game to become conference champions. They were invited to the Hawaii Bowl, where they defeated Nevada, 24–17.