The 2010 Irwin Tools Night Race was a NASCAR Sprint Cup Series stock car race that was held on August 21, 2010 at Bristol Motor Speedway in Bristol, Tennessee. Contested over 500 laps, it was the twenty-fourth race of the 2010 Sprint Cup Series season. Kyle Busch of Joe Gibbs Racing won the race, while David Reutimann finished second, and Jamie McMurray clinched third.