The 2008 Glenrothes by-election was a by-election held in Scotland on 6 November 2008 to elect a new Member of Parliament (MP) for the House of Commons constituency of Glenrothes in Fife, Scotland. The seat fell vacant when the previous MP, John MacDougall (Labour), died of pleural mesothelioma on 13 August 2008, aged 60. Pleural Mesothelioma is a rare form of lung cancer caused by prolonged exposure to asbestos. The by-election was won by Lindsay Roy of the Labour Party.