The 1980 United States Senate election in Alabama took place on November 4, 1980, alongside other elections to the United States Senate in other states as well as elections to the United States House of Representatives and various state and local elections. Incumbent Democratic U.S. Senator Donald Stewart, elected in a special election to finish the term of the seat left vacant by the death of Senator James B. Allen, decided to run for a full term, but was defeated in the primary by Jim Folsom. In November, Folsom narrowly lost the general election to Republican Jeremiah Denton.