The 1925 Tulane Green Wave football team represented the Tulane Green Wave of Tulane University in the sport of American football during the 1925 Southern Conference football season. Tulane shut out 6 of its 10 opponents, with its only blemish a tie to Missouri Valley champion Missouri. For the second year in a row, Tulane set a school record for wins in a season. Most notable was the defeat of Northwestern, a game which helped herald the arrival of Southern football. The team was ranked No. 6 in the nation in the Dickinson System ratings released in January 1926.