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Statements

Subject Item
dbr:Antibody-dependent_enhancement
dbo:wikiPageWikiLink
dbr:CD32
Subject Item
dbr:Time_Paradox
dbo:wikiPageWikiLink
dbr:CD32
Subject Item
dbr:Zool
dbo:wikiPageWikiLink
dbr:CD32
dbp:platforms
dbr:CD32
dbo:computingPlatform
dbr:CD32
Subject Item
dbr:Fc_receptor
dbo:wikiPageWikiLink
dbr:CD32
Subject Item
dbr:List_of_Codemasters_video_games
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dbr:CD32
Subject Item
dbr:List_of_Take-Two_Interactive_games
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dbr:CD32
Subject Item
dbr:Trolls_(video_game)
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dbr:CD32
Subject Item
dbr:Bureau_13_(video_game)
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dbr:CD32
Subject Item
dbr:CD32
rdf:type
yago:Part113809207 wikidata:Q8054 yago:Macromolecule114944888 yago:Bunch107959943 yago:PhysicalEntity100001930 yago:Group100031264 yago:Unit109465459 umbel-rc:ProteinMolecule owl:Thing dbo:Biomolecule yago:WikicatClustersOfDifferentiation dbo:Protein yago:Thing100002452 yago:Material114580897 yago:Relation100031921 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Compound114818238 yago:Substance100019613 wikidata:Q206229 yago:Protein114728724 yago:Matter100020827 yago:Agglomeration107959269 yago:Chemical114806838 yago:Abstraction100002137 yago:Collection107951464
rdfs:label
CD32 CD32 (proteina) CD32
rdfs:comment
Il CD32 è una glicoproteina di membrana presente sui linfociti B e sui macrofagi. Il suo nome FCγRII è indicativo della sua funzione ovvero recettore per la parte costante delle immunoglobuline di tipo γ con affinità intermedia (mentre ha affinità alta e bassa). CD32 هوَ بروتين يُشَفر بواسطة جين CD32 في الإنسان. CD32 (cluster of differentiation 32), also known as FcγRII or FCGR2, is a surface receptor glycoprotein belonging to the Ig gene superfamily. CD32 can be found on the surface of a variety of immune cells. CD32 has a low-affinity for the Fc region of IgG antibodies in monomeric form, but high affinity for IgG immune complexes. CD32 has two major functions: cellular response regulation, and the uptake of immune complexes. Cellular responses regulated by CD32 include phagocytosis, cytokine stimulation, and endocytic transport. Dysregulated CD32 is associated with different forms of autoimmunity, including systemic lupus erythematosus. In humans, there are three major CD32 subtypes: CD32A, CD32B, and CD32C. While CD32A and CD32C are involved in activating cellular responses, CD32B is inhibitor
foaf:name
Fc fragment of IgG, low affinity IIb, receptor (CD32) Fc fragment of IgG, low affinity IIc, receptor for (CD32) Fc fragment of IgG, low affinity IIa, receptor (CD32)
dbp:name
dbr:FCGR2B dbr:FCGR2A Fc fragment of IgG, low affinity IIc, receptor for
foaf:depiction
n10:CD32ray.png
dcterms:subject
dbc:Clusters_of_differentiation dbc:Fc_receptors
dbo:wikiPageID
245408
dbo:wikiPageRevisionID
1114390846
dbo:wikiPageWikiLink
dbr:Immunoglobulin_G dbr:Autoimmunity dbr:Fragment_crystallizable_region dbr:Immunological_memory dbr:Neutrophil dbr:Platelet_factor_4 dbr:Fc-gamma_receptor dbr:Clathrin dbr:Antibody-dependent_cellular_cytotoxicity dbr:FCGR2A dbr:FCGR2B dbr:Dendritic_cell dbr:Rheumatoid_arthritis dbr:Systemic_lupus_erythematosus dbr:Escherichia_coli dbr:Eosinophil dbr:Endocytosis dbr:IgG3 dbr:Follicular_dendritic_cells dbr:IgG4 dbr:Immunoreceptor_tyrosine-based_activation_motif dbr:Immunoreceptor_tyrosine-based_inhibitory_motif dbr:Cytokine dbr:Heparin-induced_thrombocytopenia dbr:Langerhans_cell dbr:Phagocytosis dbr:Monocyte dbr:Natural_killer_cell dbr:Transmembrane_protein dbr:Opsonin n16:pseudogene) dbr:Phosphorylation dbr:Smooth_muscle dbr:Megakaryocyte dbr:Monoclonal_antibody dbr:Antibody dbr:B-cell_lymphoma dbr:Glycoprotein dbr:Macrophage dbr:Antigen_presentation dbr:T_helper_cell dbr:B_cell dbr:Immune_complex dbr:Map_kinase dbr:B7_(protein) dbr:Memory_B_cell dbc:Clusters_of_differentiation dbr:SH2_domain dbr:Mast_cell dbr:Basophil dbr:Liver_sinusoidal_endothelial_cell dbr:Immunoglobulin_domain dbr:B-cell_receptor dbc:Fc_receptors dbr:Platelet dbr:Salivary_gland dbr:IgG1 dbr:IgG2
owl:sameAs
dbpedia-it:CD32_(proteina) n15:4vPXZ dbpedia-tr:CD32 freebase:m.01kjh4 yago-res:CD32 dbpedia-ar:CD32 wikidata:Q769866
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dbt:Short_description dbt:Reflist dbt:MeshName dbt:Immune_receptors dbt:About dbt:Clusters_of_differentiation dbt:Infobox_protein
dbo:thumbnail
n10:CD32ray.png?width=300
dbp:omim
146790 604590
dbp:altsymbols
FCG2, FCGR2 FCG2, FCGR2A1, FCGR2
dbp:caption
Crystal structure of the human fcgamma-receptor IIb ectodomain .
dbp:symbol
FCGR2C dbr:FCGR2A dbr:FCGR2B
dbp:uniprot
P12318 P31995 P31994
dbo:abstract
Il CD32 è una glicoproteina di membrana presente sui linfociti B e sui macrofagi. Il suo nome FCγRII è indicativo della sua funzione ovvero recettore per la parte costante delle immunoglobuline di tipo γ con affinità intermedia (mentre ha affinità alta e bassa). CD32 (cluster of differentiation 32), also known as FcγRII or FCGR2, is a surface receptor glycoprotein belonging to the Ig gene superfamily. CD32 can be found on the surface of a variety of immune cells. CD32 has a low-affinity for the Fc region of IgG antibodies in monomeric form, but high affinity for IgG immune complexes. CD32 has two major functions: cellular response regulation, and the uptake of immune complexes. Cellular responses regulated by CD32 include phagocytosis, cytokine stimulation, and endocytic transport. Dysregulated CD32 is associated with different forms of autoimmunity, including systemic lupus erythematosus. In humans, there are three major CD32 subtypes: CD32A, CD32B, and CD32C. While CD32A and CD32C are involved in activating cellular responses, CD32B is inhibitory. CD32 هوَ بروتين يُشَفر بواسطة جين CD32 في الإنسان.
dbp:arm
q
dbp:band
23
dbp:chromosome
1
dbp:entrezgene
2212 2213 9103
dbp:hgncid
3616 3618 15626
dbp:refseq
NM_201563 NM_004001 NM_021642
gold:hypernym
dbr:Protein
dbo:arm
q
dbo:band
23
dbo:chromosome
1
dbo:entrezgene
2212 9103 2213
dbo:hgncid
3618 15626 3616
dbo:refseq
NM_021642 NM_004001 NM_201563
dbo:uniprot
P31994 P31995 P12318
prov:wasDerivedFrom
wikipedia-en:CD32?oldid=1114390846&ns=0
dbo:wikiPageLength
11034
dbo:omim
146790 604590
dbo:symbol
FCG2, FCGR2A1, FCGR2 FCG2, FCGR2 FCGR2A FCGR2C FCGR2B
foaf:isPrimaryTopicOf
wikipedia-en:CD32
Subject Item
dbr:FCGR2A
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dbr:CD32
Subject Item
dbr:FCGR2B
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dbr:CD32
Subject Item
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dbr:CD32
Subject Item
dbr:Lymph_node_stromal_cell
dbo:wikiPageWikiLink
dbr:CD32
Subject Item
dbr:Non-catalytic_tyrosine-phosphorylated_receptor
dbo:wikiPageWikiLink
dbr:CD32
Subject Item
dbr:FcγRII
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dbr:CD32
dbo:wikiPageRedirects
dbr:CD32
Subject Item
wikipedia-en:CD32
foaf:primaryTopic
dbr:CD32