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Statements

Subject Item: dbr:JAM2
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:Addressin
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:Junctional_adhesion_molecule
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:Follicular_dendritic_cells
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:Integrin
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:Natalizumab
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:Marginal_zone_B-cell
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:VCAM-1
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:VLA-4
rdf:type: wikidata:Q8054 owl:Thing dbo:ChemicalCompound dbo:Biomolecule dbo:Protein wikidata:Q206229
rdfs:label: VLA-4 VLA-4
rdfs:comment: VLA-4 (англ. Very Late Antigen-4; интегрин α4β1) — мембранный белок, гетеродимерный интегриновый рецептор подсемейства β1-интегринов (рецепторы VLA), состоящий из альфа-цепи α4 (CD49d) и бета-цепи β1 (CD29). Играет роль в адгезии лейкоцитов на участке воспаления. Лигандом этого рецептора является молекула клеточной адгезии VCAM-1, экспрессируемая активированными эндотелиальными клетками. Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the beta 1 subunit is 150 kDa.
dbp:name: dbr:CD49d dbr:CD29
foaf:depiction: n16:VLA-4_Figure.jpg
dct:subject: dbc:Integrins
dbo:wikiPageID: 10247050
dbo:wikiPageRevisionID: 1116903802
dbo:wikiPageWikiLink: dbr:Endothelium dbr:Talin_(protein) n10:VLA-4_Figure.jpg dbr:VCAM-1 dbr:Natural_killer_cell dbr:Natalizumab dbr:Progenitor_cell dbr:Neutrophil dbr:Progressive_multifocal_leukoencephalopathy dbr:Ligand dbr:CD29 dbr:T-cells dbr:Monocyte dbr:Integrin dbr:Multiple_sclerosis dbr:Eosinophil dbr:CD49d dbr:Cell_adhesion dbc:Integrins dbr:Fibronectin dbr:Stromal_cell-derived_factor_1 dbr:Stem_cell dbr:Blood_brain_barrier dbr:White_blood_cell dbr:Lymphocyte dbr:Protein_dimer dbr:Autoimmune_disease
dbo:wikiPageExternalLink: n13:index.shtml n20:index.shtml n22:report.cgi%3Freport=compl_overview&compl_acc=cc00000018
owl:sameAs: wikidata:Q50257813 n11:4f9Wd dbpedia-fa:VLA-4 freebase:m.02q6dwv dbpedia-ru:VLA-4
dbp:wikiPageUsesTemplate: dbt:Reflist dbt:Cell_adhesion_molecules dbt:Infobox_protein dbt:Integrins dbt:MeshName dbt:Webarchive
dbo:thumbnail: n16:VLA-4_Figure.jpg?width=300
dbp:omim: 192975 135630
dbp:altnames: Fibronectin receptor subunit beta CD49 antigen-like family member D
dbp:altsymbols: CD29
dbp:date: 2014-12-11
dbp:symbol: dbr:CD29 dbr:CD49d
dbp:uniprot: P05556 P13612
dbp:url: n13:index.shtml
dbo:abstract: VLA-4 (англ. Very Late Antigen-4; интегрин α4β1) — мембранный белок, гетеродимерный интегриновый рецептор подсемейства β1-интегринов (рецепторы VLA), состоящий из альфа-цепи α4 (CD49d) и бета-цепи β1 (CD29). Играет роль в адгезии лейкоцитов на участке воспаления. Лигандом этого рецептора является молекула клеточной адгезии VCAM-1, экспрессируемая активированными эндотелиальными клетками. Integrin α4β1 (very late antigen-4) is an integrin dimer. It is composed of CD49d (alpha 4) and CD29 (beta 1). The alpha 4 subunit is 155 kDa, and the beta 1 subunit is 150 kDa.
dbp:arm: p q
dbp:band: 11.22 31.3
dbp:chromosome: 10 2
dbp:entrezgene: 3688 3676
dbp:hgncid: 6153 6140
dbp:refseq: NP_000876 NP_002202
gold:hypernym: dbr:Dimer
dbo:arm: q
dbo:band: 31.3
dbo:chromosome: 2
dbo:entrezgene: 3676
dbo:hgncid: 6140
dbo:refseq: NP_000876
dbo:uniprot: P13612
prov:wasDerivedFrom: wikipedia-en:VLA-4?oldid=1116903802&ns=0
dbo:wikiPageLength: 9128
dbo:omim: 192975
dbo:symbol: ITGA4
foaf:isPrimaryTopicOf: wikipedia-en:VLA-4

Subject Item: dbr:Outline_of_immunology
dbo:wikiPageWikiLink: dbr:VLA-4

Subject Item: dbr:VLA4
dbo:wikiPageWikiLink: dbr:VLA-4
dbo:wikiPageRedirects: dbr:VLA-4

Subject Item: dbr:Very_late_antigen-4
dbo:wikiPageWikiLink: dbr:VLA-4
dbo:wikiPageRedirects: dbr:VLA-4

Subject Item: dbr:Integrin_alpha4beta1
dbo:wikiPageWikiLink: dbr:VLA-4
dbo:wikiPageRedirects: dbr:VLA-4

Subject Item: dbr:Α4β1
dbo:wikiPageWikiLink: dbr:VLA-4
dbo:wikiPageRedirects: dbr:VLA-4

Subject Item: wikipedia-en:VLA-4
foaf:primaryTopic: dbr:VLA-4