This HTML5 document contains 30 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
dbohttp://dbpedia.org/ontology/
foafhttp://xmlns.com/foaf/0.1/
n14https://global.dbpedia.org/id/
dbthttp://dbpedia.org/resource/Template:
rdfshttp://www.w3.org/2000/01/rdf-schema#
freebasehttp://rdf.freebase.com/ns/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
wikipedia-enhttp://en.wikipedia.org/wiki/
dbphttp://dbpedia.org/property/
dbchttp://dbpedia.org/resource/Category:
provhttp://www.w3.org/ns/prov#
xsdhhttp://www.w3.org/2001/XMLSchema#
wikidatahttp://www.wikidata.org/entity/
goldhttp://purl.org/linguistics/gold/
dbrhttp://dbpedia.org/resource/

Statements

Subject Item
dbr:Epigenetics
dbo:wikiPageWikiLink
dbr:Somatic_epitype
Subject Item
dbr:Central_dogma_of_molecular_biology
dbo:wikiPageWikiLink
dbr:Somatic_epitype
Subject Item
dbr:Somatic_epitype
rdf:type
dbo:Disease
rdfs:label
Somatic epitype
rdfs:comment
A somatic epitype is a non-heritable epigenetic alteration in a gene. It is similar to conventional epigenetics in that it does not involve changes in the DNA primary sequence. Physically, the somatic epitype corresponds to changes in DNA methylation, oxidative damage (replacement of GTP with oxo-8-dGTP), or changes in DNA-chromatin structure that are not reversed by normal cellular or nuclear repair mechanisms. Somatic epitypes alter gene expression levels without altering the amino acid sequence of the expressed protein. Current research suggests that somatic epitypes can be altered both before and after birth, and this alteration can be in response to exposure to heavy metals (such as lead), differences in maternal care, or nutritional or behavioral stress. There is no indication that s
dcterms:subject
dbc:DNA dbc:Epigenetics
dbo:wikiPageID
8536253
dbo:wikiPageRevisionID
1015155009
dbo:wikiPageWikiLink
dbr:Guanosine_triphosphate dbr:DNA dbr:Methylation dbr:Epigenetics dbr:Lead dbr:Epigenetic dbc:Epigenetics dbc:DNA dbr:Chromatin
owl:sameAs
wikidata:Q7559240 freebase:m.02770lv n14:4vboz
dbp:wikiPageUsesTemplate
dbt:Genetics-stub dbt:Cite_journal
dbo:abstract
A somatic epitype is a non-heritable epigenetic alteration in a gene. It is similar to conventional epigenetics in that it does not involve changes in the DNA primary sequence. Physically, the somatic epitype corresponds to changes in DNA methylation, oxidative damage (replacement of GTP with oxo-8-dGTP), or changes in DNA-chromatin structure that are not reversed by normal cellular or nuclear repair mechanisms. Somatic epitypes alter gene expression levels without altering the amino acid sequence of the expressed protein. Current research suggests that somatic epitypes can be altered both before and after birth, and this alteration can be in response to exposure to heavy metals (such as lead), differences in maternal care, or nutritional or behavioral stress. There is no indication that somatic epitypes are heritable in a conventional epigenetic fashion. Some research suggests that methylation levels (and gene expression) can be reversed for some somatic epitypes by alterations in environmental factors such as diet.
gold:hypernym
dbr:Alteration
prov:wasDerivedFrom
wikipedia-en:Somatic_epitype?oldid=1015155009&ns=0
dbo:wikiPageLength
1723
foaf:isPrimaryTopicOf
wikipedia-en:Somatic_epitype
Subject Item
dbr:Reprogramming
dbo:wikiPageWikiLink
dbr:Somatic_epitype
Subject Item
wikipedia-en:Somatic_epitype
foaf:primaryTopic
dbr:Somatic_epitype