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Statements

Subject Item
n2:R12
rdf:type
dbo:ChemicalCompound
rdfs:label
Small nucleolar RNA Z152/R70/R12
rdfs:comment
In molecular biology, Small nucleolar RNA Z152 (homologous to R70 and R12) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.snoRNA Z152 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.Plant snoRNA Z152 was identified in screens of Oryza sativa and Arabidopsis thaliana.
dbp:name
Small nucleolar RNA Z152/R70/R12/
foaf:depiction
n10:RF00350.jpg
dcterms:subject
dbc:Small_nuclear_RNA
dbo:wikiPageID
12421354
dbo:wikiPageRevisionID
1052199428
dbo:wikiPageWikiLink
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dbo:thumbnail
n10:RF00350.jpg?width=300
dbp:caption
Predicted secondary structure and sequence conservation of snoZ152
dbp:id
RF00350
dbp:symbol
snoZ152
dbo:abstract
In molecular biology, Small nucleolar RNA Z152 (homologous to R70 and R12) is a non-coding RNA (ncRNA) molecule which functions in the modification of other small nuclear RNAs (snRNAs). This type of modifying RNA is usually located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.snoRNA Z152 belongs to the C/D box class of snoRNAs which contain the conserved sequence motifs known as the C box (UGAUGA) and the D box (CUGA). Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs.Plant snoRNA Z152 was identified in screens of Oryza sativa and Arabidopsis thaliana.
dbp:rfam
RF00350
dbp:rnaType
Gene; snRNA; snoRNA; CD-box
gold:hypernym
dbr:Molecule
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n8:R12?oldid=1052199428&ns=0
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2954
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n2:R12
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n2:R12
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dbr:SnoRNA_Z152
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