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Statements

Subject Item
dbr:Small_nucleolar_RNA_SNORD99
rdf:type
dbo:ChemicalCompound
rdfs:label
Small nucleolar RNA SNORD99
rdfs:comment
In molecular biology, Small Nucleolar RNA SNORD99 (also known as HBII-420) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA.
dbp:name
SNORD99 Small Nucleolar RNA SNORD99
foaf:depiction
n14:RF00608.jpg
dct:subject
dbc:Non-coding_RNA
dbo:wikiPageID
13629364
dbo:wikiPageRevisionID
1052178854
dbo:wikiPageWikiLink
dbr:Gene dbr:SnoRNA dbr:Ribosomal_RNA dbr:U98_small_nucleolar_RNA dbc:Non-coding_RNA dbr:Nucleolus dbr:Non-coding_RNA dbr:Eukaryota dbr:Sequence_conservation dbr:Molecular_biology dbr:Secondary_structure dbr:Small_nucleolar_RNA_SNORA61 dbr:Small_nucleolar_RNA dbr:Small_nucleolar_RNA_SNORA44 dbr:Small_nuclear_RNA dbr:Methylation
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wikidata:Q7543414 freebase:m.03ccbn3 n17:4v1H3
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dbt:Reflist dbt:Small_nucleolar_RNA dbt:Rfam dbt:GO dbt:Molecular-cell-biology-stub dbt:SO dbt:Infobox_rfam dbt:SnoRNABase
dbo:thumbnail
n14:RF00608.jpg?width=300
dbp:caption
Predicted secondary structure and sequence conservation of SNORD99
dbp:id
RF00608 HBII-420
dbp:symbol
SNORD99
dbo:abstract
In molecular biology, Small Nucleolar RNA SNORD99 (also known as HBII-420) is a non-coding RNA (ncRNA) molecule which functions in the biogenesis (modification) of other small nuclear RNAs (snRNAs). This type of modifying RNA is located in the nucleolus of the eukaryotic cell which is a major site of snRNA biogenesis. It is known as a small nucleolar RNA (snoRNA) and also often referred to as a guide RNA. SNORD99 belongs to the C/D box class of snoRNAs which contain the C (UGAUGA) and D (CUGA) box motifs. Most of the members of the box C/D family function in directing site-specific 2'-O-methylation of substrate RNAs. SNORD99 is predicted to guide the 2'O-ribose methylation of 28S ribosomal RNA at residue A2774. In the human genome this snoRNA shares the same host gene with the three H/ACA box snoRNAs ACA16, ACA44 and ACA61.
dbp:rfam
RF00608
dbp:rnaType
Gene; snRNA; snoRNA; C/D-box
gold:hypernym
dbr:Molecule
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wikipedia-en:Small_nucleolar_RNA_SNORD99?oldid=1052178854&ns=0
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2604
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wikipedia-en:Small_nucleolar_RNA_SNORD99
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Subject Item
wikipedia-en:Small_nucleolar_RNA_SNORD99
foaf:primaryTopic
dbr:Small_nucleolar_RNA_SNORD99