This HTML5 document contains 89 embedded RDF statements represented using HTML+Microdata notation.

The embedded RDF content will be recognized by any processor of HTML5 Microdata.

Namespace Prefixes

PrefixIRI
dctermshttp://purl.org/dc/terms/
dbohttp://dbpedia.org/ontology/
n8http://dbpedia.org/resource/File:
foafhttp://xmlns.com/foaf/0.1/
n14https://global.dbpedia.org/id/
yagohttp://dbpedia.org/class/yago/
dbthttp://dbpedia.org/resource/Template:
rdfshttp://www.w3.org/2000/01/rdf-schema#
freebasehttp://rdf.freebase.com/ns/
n21http://yago-knowledge.org/resource/Nucleotide_pyrophosphatase/
n5http://dbpedia.org/resource/Nucleotide_Pyrophosphatase/
n4http://commons.wikimedia.org/wiki/Special:FilePath/
rdfhttp://www.w3.org/1999/02/22-rdf-syntax-ns#
owlhttp://www.w3.org/2002/07/owl#
n15http://en.wikipedia.org/wiki/Nucleotide_pyrophosphatase/
n2http://dbpedia.org/resource/Nucleotide_pyrophosphatase/
dbchttp://dbpedia.org/resource/Category:
dbphttp://dbpedia.org/property/
provhttp://www.w3.org/ns/prov#
xsdhhttp://www.w3.org/2001/XMLSchema#
goldhttp://purl.org/linguistics/gold/
wikidatahttp://www.wikidata.org/entity/
dbrhttp://dbpedia.org/resource/

Statements

Subject Item
dbr:NPP
dbo:wikiPageWikiLink
n2:phosphodiesterase
Subject Item
n2:phosphodiesterase
rdf:type
yago:Material114580897 yago:PhysicalEntity100001930 dbo:Biomolecule dbo:Enzyme yago:Compound114818238 owl:Thing yago:OrganicCompound114727670 yago:Macromolecule114944888 yago:Relation100031921 yago:Abstraction100002137 yago:Matter100020827 wikidata:Q206229 yago:Enzyme114732946 yago:Part113809207 yago:Molecule114682133 yago:Unit109465459 yago:Catalyst114723628 yago:Chemical114806838 yago:Activator114723079 yago:Thing100002452 yago:Substance100019613 yago:Protein114728724 wikidata:Q8047 yago:WikicatEnzymesOfKnownStructure
rdfs:label
Nucleotide pyrophosphatase/phosphodiesterase
rdfs:comment
Nucleotide pyrophosphatase/phosphodiesterase (NPP) is a class of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. NPP belongs to the alkaline phosphatase (AP) superfamily of enzymes. Humans express seven known NPP isoforms, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. In eukaryotes, most NPPs are located in the cell membrane and hydrolyze extracellular phosphate diesters to affect a wide variety of biological processes. Bacterial NPP is thought to localize to the periplasm.
foaf:name
Nucleotide pyrophosphatase/phosphodiesterase (NPP)
dbp:name
Nucleotide pyrophosphatase/phosphodiesterase
foaf:depiction
n4:NPPScheme.png n4:NPP_More-OFerall-Jenck.png n4:Nucleotide_pyrophosphatase.png n4:Nucleotide_pyrophosphatase_close_up.png n4:NPPActiveSite.png
dcterms:subject
dbc:Protein_structure dbc:Enzymes_of_known_structure dbc:Biochemistry
dbo:wikiPageID
34941120
dbo:wikiPageRevisionID
1081464273
dbo:wikiPageWikiLink
n8:Nucleotide_pyrophosphatase_close_up.png dbc:Enzymes_of_known_structure dbr:Calcium_phosphate n2:phosphodiesterase_I dbr:Enzyme_substrate_(biology) dbr:Phosphate dbr:Enzymes n8:NPPScheme.png n8:NPP_More-OFerall-Jenck.png dbr:Phospholipid dbr:Molecular_dynamics dbr:T_cell dbr:Isoforms dbr:Angiogenesis dbc:Biochemistry dbr:Diabetes_mellitus_type_2 dbr:Metastasis dbr:Transition_state dbr:Calcification dbr:Autotaxin dbr:Diester n8:NPPActiveSite.png dbr:Insulin_receptor dbr:Nucleophilic_substitution dbr:SN2_reaction dbr:Reaction_intermediate dbr:Nucleotide dbr:Chondrocalcinosis dbr:Alkaline_phosphatase dbr:Bile dbc:Protein_structure
owl:sameAs
n14:4t4zL wikidata:Q7068263 n21:phosphodiesterase freebase:m.0j42sxp
dbp:wikiPageUsesTemplate
dbt:Enzyme dbt:Reflist
dbo:thumbnail
n4:Nucleotide_pyrophosphatase.png?width=300
dbp:caption
The overall dimeric structure of NPP in Xanthomonas axonopodis pv. citri str. 306 . This enzyme relies on the catalytic ability of 2 Zn2+ atoms in the catalytic core, which are shown in white.
dbp:ecNumber
3.6
dbo:abstract
Nucleotide pyrophosphatase/phosphodiesterase (NPP) is a class of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. NPP belongs to the alkaline phosphatase (AP) superfamily of enzymes. Humans express seven known NPP isoforms, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. In eukaryotes, most NPPs are located in the cell membrane and hydrolyze extracellular phosphate diesters to affect a wide variety of biological processes. Bacterial NPP is thought to localize to the periplasm.
gold:hypernym
dbr:Enzymes
prov:wasDerivedFrom
n15:phosphodiesterase?oldid=1081464273&ns=0
dbo:wikiPageLength
19851
dbo:ecNumber
3.6.1.9
foaf:isPrimaryTopicOf
n15:phosphodiesterase
Subject Item
n5:Phosphodiesterase_(NPP)
dbo:wikiPageWikiLink
n2:phosphodiesterase
dbo:wikiPageRedirects
n2:phosphodiesterase
Subject Item
dbr:Tyrosinase
dbo:wikiPageWikiLink
n2:phosphodiesterase
Subject Item
n15:phosphodiesterase
foaf:primaryTopic
n2:phosphodiesterase