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Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. L-tyrosine + 2-oxoglutarate 4-hydroxyphenylpyruvate + L-glutamate In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is known as type II tyrosinemia, wherein there is an abundance of tyrosine as a result of tyrosine failing to undergo an aminotransferase reaction to form 4-hydroxyphenylpyruvate.

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dbo:abstract
  • La tirosina aminotransferasa o tirosina transaminasa (EC 2.6.1.5) es una enzima que cataliza la conversión de tirosina a 4-hidroxifenilpiruvato.​ L-tirosina + 2-oxoglutarato 4-hidroxifenilpiruvato + L-glutamato En humanos, la proteína tirosina aminotransferasa se encuentra codificada por el gen TAT. Una deficiencia de esta enzima en seres humanos produce la enfermedad conocida como tirosinemia tipo II, donde existe un exceso de tirosina en circulación como resultado de que la tirosina falla en convertirse en 4-hidroxifenilpiruvato.​ (es)
  • Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. L-tyrosine + 2-oxoglutarate 4-hydroxyphenylpyruvate + L-glutamate In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is known as type II tyrosinemia, wherein there is an abundance of tyrosine as a result of tyrosine failing to undergo an aminotransferase reaction to form 4-hydroxyphenylpyruvate. (en)
dbo:ecNumber
  • 2.6.1.5
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  • 1118756782 (xsd:integer)
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dbp:caption
  • Human tyrosine aminotransferase complexed with pyridoxal phosphate . (en)
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  • 9014 (xsd:integer)
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  • 2.600000 (xsd:double)
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  • 80130 (xsd:integer)
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  • 2 (xsd:integer)
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  • Tyrosine transaminase (en)
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  • La tirosina aminotransferasa o tirosina transaminasa (EC 2.6.1.5) es una enzima que cataliza la conversión de tirosina a 4-hidroxifenilpiruvato.​ L-tirosina + 2-oxoglutarato 4-hidroxifenilpiruvato + L-glutamato En humanos, la proteína tirosina aminotransferasa se encuentra codificada por el gen TAT. Una deficiencia de esta enzima en seres humanos produce la enfermedad conocida como tirosinemia tipo II, donde existe un exceso de tirosina en circulación como resultado de que la tirosina falla en convertirse en 4-hidroxifenilpiruvato.​ (es)
  • Tyrosine aminotransferase (or tyrosine transaminase) is an enzyme present in the liver and catalyzes the conversion of tyrosine to 4-hydroxyphenylpyruvate. L-tyrosine + 2-oxoglutarate 4-hydroxyphenylpyruvate + L-glutamate In humans, the tyrosine aminotransferase protein is encoded by the TAT gene. A deficiency of the enzyme in humans can result in what is known as type II tyrosinemia, wherein there is an abundance of tyrosine as a result of tyrosine failing to undergo an aminotransferase reaction to form 4-hydroxyphenylpyruvate. (en)
rdfs:label
  • Tirosina aminotransferasa (es)
  • Tyrosine aminotransferase (en)
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  • Tyrosine transaminase (en)
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