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- In enzymology, a thymidylate synthase (FAD) (EC 2.1.1.148) is an enzyme that catalyzes the chemical reaction 5,10-methylenetetrahydrofolate + dUMP + FADH2 dTMP + tetrahydrofolate + FAD The 3 substrates of this enzyme are 5,10-methylenetetrahydrofolate, dUMP, and FADH2, whereas its 3 products are dTMP, tetrahydrofolate, and FAD. This enzyme belongs to the family of transferases, to be specific those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is 5,10-methylenetetrahydrofolate,FADH2:dUMP C-methyltransferase. Other names in common use include Thy1, and ThyX. This enzyme participates in pyrimidine metabolism and one carbon pool by folate. Most organisms, including humans, use the - or TYMS-encoded classic thymidylate synthase whereas some bacteria use the similar (FDTS) instead. (en)
- チミジル酸シンターゼ (FAD) (英:Thymidylate synthase (FAD))(EC 2.1.1.148)は、次の反応を触媒する酵素である。 5,10-メチレンテトラヒドロ葉酸 + デオキシウリジン一リン酸（dUMP） + FADH2 チミジル酸（dTMP） + ジヒドロ葉酸 + FAD この酵素は、特に一炭素基を移転させるメチル転移酵素であり転移酵素グループに属する。 (ja)
- La timidilato sintasi (FAD) è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: 5,10-metilenetetraidrofolato + dUMP + FADH2 ⇄ d + tetraidrofolato + FAD Il FMN può sostituire FAD. La reazione descritta sopra è diversa da quella della classica timidilato sintasi, o ThyA (numero EC 2.1.1.45). (it)
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- 2719 (xsd:nonNegativeInteger)
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- Flavin-dependent thymidylate synthase tetramer, Thermotoga maritima (en)
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- thymidylate synthase (en)
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- チミジル酸シンターゼ (FAD) (英:Thymidylate synthase (FAD))(EC 2.1.1.148)は、次の反応を触媒する酵素である。 5,10-メチレンテトラヒドロ葉酸 + デオキシウリジン一リン酸（dUMP） + FADH2 チミジル酸（dTMP） + ジヒドロ葉酸 + FAD この酵素は、特に一炭素基を移転させるメチル転移酵素であり転移酵素グループに属する。 (ja)
- La timidilato sintasi (FAD) è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: 5,10-metilenetetraidrofolato + dUMP + FADH2 ⇄ d + tetraidrofolato + FAD Il FMN può sostituire FAD. La reazione descritta sopra è diversa da quella della classica timidilato sintasi, o ThyA (numero EC 2.1.1.45). (it)
- In enzymology, a thymidylate synthase (FAD) (EC 2.1.1.148) is an enzyme that catalyzes the chemical reaction 5,10-methylenetetrahydrofolate + dUMP + FADH2 dTMP + tetrahydrofolate + FAD The 3 substrates of this enzyme are 5,10-methylenetetrahydrofolate, dUMP, and FADH2, whereas its 3 products are dTMP, tetrahydrofolate, and FAD. Most organisms, including humans, use the - or TYMS-encoded classic thymidylate synthase whereas some bacteria use the similar (FDTS) instead. (en)
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- Timidilato sintasi (FAD) (it)
- チミジル酸シンターゼ(FAD) (ja)
- Thymidylate synthase (FAD) (en)
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- thymidylate synthase (FAD) (en)
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