About: ST-1936

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

ST-1936 (2-methyl-5-chloro-N,N-dimethyltryptamine) is a tryptamine derivative which is used in scientific research. It acts as a selective 5-HT6 receptor agonist, with a Ki of 13 nM, and much weaker action at 5-HT2B and 5-HT7 subtypes. In animal studies it has been found to increase dopamine and noradrenaline mediated signalling but decreases glutamatergic transmission, and has antidepressant effects.

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dbo:abstract
  • ST-1936 (2-methyl-5-chloro-N,N-dimethyltryptamine) is a tryptamine derivative which is used in scientific research. It acts as a selective 5-HT6 receptor agonist, with a Ki of 13 nM, and much weaker action at 5-HT2B and 5-HT7 subtypes. In animal studies it has been found to increase dopamine and noradrenaline mediated signalling but decreases glutamatergic transmission, and has antidepressant effects. (en)
dbo:casNumber
  • 1210-81-7
dbo:chEMBL
  • 365751
dbo:fdaUniiCode
  • 4R5ZNV2CHC
dbo:pubchem
  • 9921064
dbo:thumbnail
dbo:wikiPageID
  • 40777228 (xsd:integer)
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  • 3289 (xsd:nonNegativeInteger)
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  • 1111220663 (xsd:integer)
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dbp:atcPrefix
  • none (en)
dbp:c
  • 13 (xsd:integer)
dbp:casNumber
  • 1210 (xsd:integer)
dbp:chembl
  • 365751 (xsd:integer)
dbp:chemspiderid
  • 8096699 (xsd:integer)
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  • 1 (xsd:integer)
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  • 17 (xsd:integer)
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  • 2 (xsd:integer)
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  • 2 (xsd:integer)
dbp:pubchem
  • 9921064 (xsd:integer)
dbp:smiles
  • CC1=CC2=CC=CC=C2N1 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • KSYMELKKLOFABL-UHFFFAOYSA-N (en)
dbp:unii
  • 4 (xsd:integer)
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dcterms:subject
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rdfs:comment
  • ST-1936 (2-methyl-5-chloro-N,N-dimethyltryptamine) is a tryptamine derivative which is used in scientific research. It acts as a selective 5-HT6 receptor agonist, with a Ki of 13 nM, and much weaker action at 5-HT2B and 5-HT7 subtypes. In animal studies it has been found to increase dopamine and noradrenaline mediated signalling but decreases glutamatergic transmission, and has antidepressant effects. (en)
rdfs:label
  • ST-1936 (en)
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foaf:isPrimaryTopicOf
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is foaf:primaryTopic of
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