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- The family of non-collagenous proteins known as SIBLING proteins, standing for small integrin-binding ligand, N-linked glycoprotein, are components of the extracellular matrix of bone and dentin. Evidence shows that these proteins play key roles in the mineralization of these tissues. The following are categorized as SIBLING proteins: 1.
* osteopontin (OPN) 2.
* bone sialoprotein (BSP) 3.
* dentin matrix protein 1 (DMP1) 4.
* dentin sialophosphoprotein (DSPP) 5.
* matrix extracellular phosphoglycoprotein (MEPE) The genes coding for members of the SIBLING protein family are similarly organized and are all located on human chromosome 4q21-23. (en)
- SIBLING蛋白是一種，是骨和牙本质的细胞外基质的组成部分。其英文部分「SIBLING」为小整联N-连接糖蛋白（small integrin-binding ligand, N-linked glycoprotein）的缩写。有证据表明SIBLING蛋白在这些组织的中起关键作用。 下列蛋白质属于SIBLING蛋白： 1.
* 骨桥蛋白 Osteopontin (OPN) 或分泌磷蛋白1 Secreted phosphoprotein 1 (SPP1)； 2.
* 骨涎蛋白 bone sialoprotein （BSP）； 3.
* 牙本质基质蛋白1 Dentin matrix protein 1 (DMP1)； 4.
* 牙本质唾液酸磷酸蛋白 Dentin sialophosphoprotein (DSPP)； 5.
* 基质细胞外磷酸糖蛋白 Matrix extracellular phosphoglycoprotein (MEPE)。 编码SIBLING家族蛋白的基因位于人类染色体4q21-23上。 (zh)
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- SIBLING蛋白是一種，是骨和牙本质的细胞外基质的组成部分。其英文部分「SIBLING」为小整联N-连接糖蛋白（small integrin-binding ligand, N-linked glycoprotein）的缩写。有证据表明SIBLING蛋白在这些组织的中起关键作用。 下列蛋白质属于SIBLING蛋白： 1.
* 骨桥蛋白 Osteopontin (OPN) 或分泌磷蛋白1 Secreted phosphoprotein 1 (SPP1)； 2.
* 骨涎蛋白 bone sialoprotein （BSP）； 3.
* 牙本质基质蛋白1 Dentin matrix protein 1 (DMP1)； 4.
* 牙本质唾液酸磷酸蛋白 Dentin sialophosphoprotein (DSPP)； 5.
* 基质细胞外磷酸糖蛋白 Matrix extracellular phosphoglycoprotein (MEPE)。 编码SIBLING家族蛋白的基因位于人类染色体4q21-23上。 (zh)
- The family of non-collagenous proteins known as SIBLING proteins, standing for small integrin-binding ligand, N-linked glycoprotein, are components of the extracellular matrix of bone and dentin. Evidence shows that these proteins play key roles in the mineralization of these tissues. The following are categorized as SIBLING proteins: 1.
* osteopontin (OPN) 2.
* bone sialoprotein (BSP) 3.
* dentin matrix protein 1 (DMP1) 4.
* dentin sialophosphoprotein (DSPP) 5.
* matrix extracellular phosphoglycoprotein (MEPE) (en)
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- SIBLING proteins (en)
- SIBLING蛋白 (zh)
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