About: Sabcomeline

Property	Value
dbo:abstract	La sabcomelina (Memric; SB-202,026) es un agonista parcial selectivo del receptor M1 que estaba en desarrollo para el tratamiento de la enfermedad de Alzheimer. Llegó a los ensayos clínicos de fase III antes de ser descontinuado debido a los malos resultados. (es) Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease. It made it to phase III clinical trials before being discontinued due to poor results. (en) サブコメリン(Sabcomeline)は、M1受容体の選択的パーシャルアゴニストで、アルツハイマー病の治療薬として開発が進められた。結果不良で開発中止になる前に第3段階の治験まで進んだ。 (ja)
dbo:casNumber	159912-53-5 159912-58-0
dbo:chEMBL	134641
dbo:fdaUniiCode	A24BK93DRR P8P92V596C
dbo:pubchem	9577995
dbo:thumbnail	wiki-commons:Special:FilePath/Sabcomeline_skeletal.svg?width=300
dbo:wikiPageID	25288860 (xsd:integer)
dbo:wikiPageLength	2014 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1094691186 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Partial_agonist dbc:Experimental_drugs dbr:Phase_III_clinical_trials dbr:Clinical_trial dbr:Muscarinic_acetylcholine_receptor_M1 dbc:Muscarinic_agonists dbr:Alvameline dbr:Alzheimer's_disease dbc:Nitriles dbr:Tazomeline dbc:Quinuclidines dbr:Binding_selectivity dbc:Oximes dbr:Milameline dbr:Xanomeline
dbp:atcPrefix	None (en)
dbp:c	10 (xsd:integer)
dbp:casNumber	159912 (xsd:integer)
dbp:chembl	134641 (xsd:integer)
dbp:chemspiderid	7852359 (xsd:integer)
dbp:h	15 (xsd:integer)
dbp:index2Label	HCl (en)
dbp:iupacName	-N-methoxyquinuclidine-3-carboximidoyl cyanide hydrochloride (en)
dbp:iupharLigand	306 (xsd:integer)
dbp:legalStatus	Never marketed (en)
dbp:n	3 (xsd:integer)
dbp:o	1 (xsd:integer)
dbp:pubchem	9577995 (xsd:integer)
dbp:smiles	C2CC1CCN2CC1\C=N\OC (en)
dbp:unii	A24BK93DRR (en) P8P92V596C (en)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Reflist dbt:Short_description dbt:Cascite dbt:Fdacite dbt:Muscarinic_acetylcholine_receptor_modulators dbt:Anti-dementia_drugs
dcterms:subject	dbc:Experimental_drugs dbc:Muscarinic_agonists dbc:Nitriles dbc:Quinuclidines dbc:Oximes
gold:hypernym	dbr:M
rdf:type	owl:Thing dbo:Place dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatMolecularFormulas yago:WikicatNitriles yago:WikicatOximes yago:Abstraction100002137 yago:Chemical114806838 yago:Communication100033020 yago:Compound114818238 yago:Formula106816935 yago:Material114580897 yago:Matter100020827 yago:Message106598915 yago:MolecularFormula106817173 yago:Nitrile114827346 yago:OrganicCompound114727670 yago:Oxime114972092 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:Drug yago:Statement106722453 yago:Substance100019613
rdfs:comment	La sabcomelina (Memric; SB-202,026) es un agonista parcial selectivo del receptor M1 que estaba en desarrollo para el tratamiento de la enfermedad de Alzheimer. Llegó a los ensayos clínicos de fase III antes de ser descontinuado debido a los malos resultados. (es) Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease. It made it to phase III clinical trials before being discontinued due to poor results. (en) サブコメリン(Sabcomeline)は、M1受容体の選択的パーシャルアゴニストで、アルツハイマー病の治療薬として開発が進められた。結果不良で開発中止になる前に第3段階の治験まで進んだ。 (ja)
rdfs:label	Sabcomelina (es) サブコメリン (ja) Sabcomeline (en)
owl:sameAs	freebase:Sabcomeline yago-res:Sabcomeline wikidata:Sabcomeline dbpedia-es:Sabcomeline dbpedia-fa:Sabcomeline dbpedia-ja:Sabcomeline dbpedia-sh:Sabcomeline dbpedia-sr:Sabcomeline https://global.dbpedia.org/id/4vBeu
prov:wasDerivedFrom	wikipedia-en:Sabcomeline?oldid=1094691186&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Sabcomeline_skeletal.svg
foaf:isPrimaryTopicOf	wikipedia-en:Sabcomeline
is dbo:wikiPageRedirects of	dbr:C10H15N3O dbr:Memric dbr:SB-202,026 dbr:SB-202026 dbr:SB202,026 dbr:SB202026
is dbo:wikiPageWikiLink of	dbr:Muscarinic_acetylcholine_receptor_M5 dbr:C10H15N3O dbr:Alvameline dbr:Tazomeline dbr:Memric dbr:Milameline dbr:Xanomeline dbr:List_of_drugs:_S–Sd dbr:SB-202,026 dbr:SB-202026 dbr:SB202,026 dbr:SB202026
is foaf:primaryTopic of	wikipedia-en:Sabcomeline