A nuclear groove is an invagination of the nuclear envelope, in the longitudinal axis. It can be present in: * Thyroid neoplasms: It is a characteristic feature of papillary thyroid carcinoma, but has also been seen in other types of thyroid neoplasms, as well as in non-neoplastic thyroid lesions. * Ovarian tumors including Brenner tumors, , and . * Breast carcinomas * Vaginal, cervical and/or * of several organs: of the urinary bladder, papillary renal cell carcinoma, of the prostate, in , and in non-epithelial tumors.
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