About: Miotine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically. Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.

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dbo:abstract	Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically. Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects. (en)
dbo:iupacName	[3-[1-(Dimethylamino)ethyl]phenyl] N-methylcarbamate (en)
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dbp:iupacname	[3-[1-ethyl]phenyl] N-methylcarbamate (en)
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rdfs:comment	Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically. Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects. (en)
rdfs:label	Miotine (en)
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