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- Medetomidin ist eine chemische Verbindung aus der Gruppe der Imidazole, die in der Tier- und Humanmedizin als Sedativum und Schmerzmittel eingesetzt wird. Das pharmakologisch wirksame Enantiomer im Racemat [1:1-Gemisch der (R)-Form und der (S)-Form] ist die (R)-(+)-Form. Das Racemat wird vor allem als wasserlösliches, weißes, kristallines Medetomidin·Hydrochlorid verwendet. (de)
- Medetomidine is a synthetic drug used as both a surgical anesthetic and analgesic. It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid. It is an α2 adrenergic agonist that can be administered as an intravenous drug solution with sterile water. It was developed by Orion Pharma. It is approved for dogs in the United States, and distributed in the United States by Pfizer Animal Health and by Novartis Animal Health in Canada under the product name Domitor. Other alpha-two agonists used in veterinary medicine include xylazine and detomidine, but their use is less common in small animal surgery. The marketed product is a racemic mixture of two stereoisomers; dexmedetomidine is the isomer with more useful effects, and is now marketed as Dexdomitor. The free base form of medetomidine is sold as Selektope for use as an antifouling substance in marine paints. (en)
- La médétomidine est un α2-agoniste utilisé en anesthésiologie vétérinaire. Il est l'un des sédatifs les plus puissants de sa classe. (fr)
- メデトミジン（英:medetomidine）とはα2アドレナリン受容体作動薬の1つ。α2受容体を活性化することにより鎮静作用、鎮痛作用、筋弛緩作用を示す。副作用として心臓の刺激伝導系の遮断による徐脈、一過性の血圧上昇に続発する心拍出量と血圧の低下を引き起こす。フィンランドのオリオン社が開発した。商品名はドミトール（Domitor、製造元はオリオン社、国内販売元は日本全薬工業）。アチパメゾールが拮抗的にメデトミジンの作用を抑制する。 船舶向け防汚塗料の有効成分としても使われている。 (ja)
- Medetomidine is een in de veterinaire anesthesiologie zeer vaak gebruikte α2-agonist. Het is een van de meest krachtige sedativa uit deze groep. (nl)
- La medetomidina è un potentissimo agonista selettivo alfa2-adrenergico. In medicina veterinaria ne è consentito l'uso solo nel cane e nel gatto. Viene associato alla ketamina per indurre un'anestesia di breve durata. (it)
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- Medetomidin ist eine chemische Verbindung aus der Gruppe der Imidazole, die in der Tier- und Humanmedizin als Sedativum und Schmerzmittel eingesetzt wird. Das pharmakologisch wirksame Enantiomer im Racemat [1:1-Gemisch der (R)-Form und der (S)-Form] ist die (R)-(+)-Form. Das Racemat wird vor allem als wasserlösliches, weißes, kristallines Medetomidin·Hydrochlorid verwendet. (de)
- La médétomidine est un α2-agoniste utilisé en anesthésiologie vétérinaire. Il est l'un des sédatifs les plus puissants de sa classe. (fr)
- メデトミジン（英:medetomidine）とはα2アドレナリン受容体作動薬の1つ。α2受容体を活性化することにより鎮静作用、鎮痛作用、筋弛緩作用を示す。副作用として心臓の刺激伝導系の遮断による徐脈、一過性の血圧上昇に続発する心拍出量と血圧の低下を引き起こす。フィンランドのオリオン社が開発した。商品名はドミトール（Domitor、製造元はオリオン社、国内販売元は日本全薬工業）。アチパメゾールが拮抗的にメデトミジンの作用を抑制する。 船舶向け防汚塗料の有効成分としても使われている。 (ja)
- Medetomidine is een in de veterinaire anesthesiologie zeer vaak gebruikte α2-agonist. Het is een van de meest krachtige sedativa uit deze groep. (nl)
- La medetomidina è un potentissimo agonista selettivo alfa2-adrenergico. In medicina veterinaria ne è consentito l'uso solo nel cane e nel gatto. Viene associato alla ketamina per indurre un'anestesia di breve durata. (it)
- Medetomidine is a synthetic drug used as both a surgical anesthetic and analgesic. It is often used as the hydrochloride salt, medetomidine hydrochloride, a crystalline white solid. It is an α2 adrenergic agonist that can be administered as an intravenous drug solution with sterile water. (en)
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| rdfs:label
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- Medetomidin (de)
- Médétomidine (fr)
- Medetomidina (it)
- Medetomidine (en)
- メデトミジン (ja)
- Medetomidine (nl)
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