About: Mapracorat

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Mapracorat (INN, code names BOL-303242-X, ZK-245186) is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs). It is in clinical trials for the topical treatment of atopic dermatitis, inflammation following cataract surgery, and allergic conjunctivitis. Preliminary investigation for the treatment of keratoconjunctivitis sicca has been conducted in cellular models.

Property	Value
dbo:abstract	Mapracorat (INN, code names BOL-303242-X, ZK-245186) is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs). It is in clinical trials for the topical treatment of atopic dermatitis, inflammation following cataract surgery, and allergic conjunctivitis. Preliminary investigation for the treatment of keratoconjunctivitis sicca has been conducted in cellular models. (en)
dbo:casNumber	887375-26-0
dbo:fdaUniiCode	145V79YBVP
dbo:kegg	D10136
dbo:pubchem	24795088
dbo:thumbnail	wiki-commons:Special:FilePath/Mapracorat_skeletal.svg?width=300
dbo:wikiPageID	28813544 (xsd:integer)
dbo:wikiPageLength	4900 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	963923281 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Cataract_surgery dbr:Bausch_&_Lomb dbr:Allergic_conjunctivitis dbc:Selective_glucocorticoid_receptor_modulators dbr:Dagrocorat dbr:Dermatology dbc:Fluoroarenes dbc:Trifluoromethyl_compounds dbr:Clinical_trial dbr:Suspension_(chemistry) dbr:AZD-5423 dbc:Immunosuppressants dbr:Eye_drops dbr:Bayer_HealthCare_Pharmaceuticals dbr:Fosdagrocorat dbr:Double_blind dbc:Quinolines dbr:International_Nonproprietary_Name dbr:Atopic_dermatitis dbc:Anti-inflammatory_agents dbc:Benzofurans dbr:Placebo dbr:Ointment dbr:Ophthalmology dbr:Keratoconjunctivitis_sicca dbr:Selective_glucocorticoid_receptor_agonist dbr:Anti-inflammatory_drug dbr:</nowiki>(2-methylquinolin-5-yl)amino]methyl]pentan-2-ol
dbp:atcPrefix	none (en)
dbp:c	25 (xsd:integer)
dbp:casNumber	887375 (xsd:integer)
dbp:chemspiderid	25104194 (xsd:integer)
dbp:f	4 (xsd:integer)
dbp:h	26 (xsd:integer)
dbp:iupacName	-111 (xsd:integer)
dbp:kegg	D10136 (en)
dbp:legalStatus	Investigational (en)
dbp:n	2 (xsd:integer)
dbp:o	2 (xsd:integer)
dbp:pubchem	24795088 (xsd:integer)
dbp:routesOfAdministration	Topical (en)
dbp:smiles	c14OCCc4cccc1CCCCNcc2ccc3C (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	VJGFOYBQOIPQFY-XMMPIXPASA-N (en)
dbp:unii	145 (xsd:integer)
dbp:verifiedfields	changed (en)
dbp:verifiedrevid	406275524 (xsd:integer)
dbp:width	250 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Antineoplastic-drug-stub dbt:As_of dbt:Dermatologic-drug-stub dbt:Drugbox dbt:Glucocorticoid_receptor_modulators dbt:Musculoskeletal-drug-stub dbt:Reflist dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Fdacite dbt:Keggcite dbt:Stdinchicite dbt:Glucocorticoids_and_antiglucocorticoids
dcterms:subject	dbc:Selective_glucocorticoid_receptor_modulators dbc:Fluoroarenes dbc:Trifluoromethyl_compounds dbc:Immunosuppressants dbc:Quinolines dbc:Anti-inflammatory_agents dbc:Benzofurans
gold:hypernym	dbr:Drug
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAnti-inflammatoryAgents yago:Agent109190918 yago:Agent114778436 yago:CausalAgent100007347 yago:Drug103247620 yago:Immunosuppressant103562958 yago:Matter100020827 yago:Medicine103740161 yago:PhysicalEntity100001930 yago:WikicatImmunosuppressants dbo:Drug yago:Substance100020090
rdfs:comment	Mapracorat (INN, code names BOL-303242-X, ZK-245186) is an anti-inflammatory drug belonging to the experimental class of selective glucocorticoid receptor agonists (SEGRAs). It is in clinical trials for the topical treatment of atopic dermatitis, inflammation following cataract surgery, and allergic conjunctivitis. Preliminary investigation for the treatment of keratoconjunctivitis sicca has been conducted in cellular models. (en)
rdfs:label	Mapracorat (en)
owl:sameAs	freebase:Mapracorat yago-res:Mapracorat wikidata:Mapracorat dbpedia-sh:Mapracorat dbpedia-sr:Mapracorat https://global.dbpedia.org/id/4rKcz
prov:wasDerivedFrom	wikipedia-en:Mapracorat?oldid=963923281&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Mapracorat_skeletal.svg
foaf:isPrimaryTopicOf	wikipedia-en:Mapracorat
is dbo:wikiPageWikiLink of	dbr:Dagrocorat dbr:AZD-5423 dbr:Nonsteroidal dbr:Fosdagrocorat dbr:Tanaproget dbr:Selective_glucocorticoid_receptor_modulator dbr:List_of_drugs:_M–Md
is foaf:primaryTopic of	wikipedia-en:Mapracorat