About: Leukotriene-C4 synthase

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The enzyme leukotriene-C4 synthase (EC 4.4.1.20) catalyzes the reaction leukotriene C4 leukotriene A4 + glutathione This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is leukotriene-C4 glutathione-lyase (leukotriene-A4-forming). Other names in common use include leukotriene C4 synthetase, LTC4 synthase, LTC4 synthetase, leukotriene A4:glutathione S-leukotrienyltransferase, (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase, (epoxide-ring-opening), (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). This enzyme participates in arachidonic acid metabolism.

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  • The enzyme leukotriene-C4 synthase (EC 4.4.1.20) catalyzes the reaction leukotriene C4 leukotriene A4 + glutathione This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is leukotriene-C4 glutathione-lyase (leukotriene-A4-forming). Other names in common use include leukotriene C4 synthetase, LTC4 synthase, LTC4 synthetase, leukotriene A4:glutathione S-leukotrienyltransferase, (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase, (epoxide-ring-opening), (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). This enzyme participates in arachidonic acid metabolism. (en)
dbo:ecNumber
  • 4.4.1.20
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  • 14246526 (xsd:integer)
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  • 3008 (xsd:nonNegativeInteger)
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  • 1104083451 (xsd:integer)
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  • Leukotriene C4 synthase dodecamer, Human (en)
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  • 90698 (xsd:integer)
dbp:ecNumber
  • 4.400000 (xsd:double)
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  • 4464 (xsd:integer)
dbp:iubmbEcNumber
  • 4 (xsd:integer)
dbp:name
  • leukotriene-C4 synthase (en)
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  • 270 (xsd:integer)
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  • The enzyme leukotriene-C4 synthase (EC 4.4.1.20) catalyzes the reaction leukotriene C4 leukotriene A4 + glutathione This enzyme belongs to the family of lyases, specifically the class of carbon-sulfur lyases. The systematic name of this enzyme class is leukotriene-C4 glutathione-lyase (leukotriene-A4-forming). Other names in common use include leukotriene C4 synthetase, LTC4 synthase, LTC4 synthetase, leukotriene A4:glutathione S-leukotrienyltransferase, (7E,9E,11Z,14Z)-(5S,6R)-5,6-epoxyicosa-7,9,11,14-tetraenoate:glutathione leukotriene-transferase, (epoxide-ring-opening), (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming). This enzyme participates in arachidonic acid metabolism. (en)
rdfs:label
  • Leukotriene-C4 synthase (en)
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foaf:name
  • leukotriene-C4 synthase (en)
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