About: Leukocyte immunoglobulin-like receptors

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The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains.They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. The human genes encoding these receptors are found in a gene cluster at chromosomal region 19q13.4. They include * LILRA1 * LILRA2 * LILRA3 * LILRA4 * LILRA5 * * LILRB1 * LILRB2 * LILRB3 * LILRB4 * LILRB5 * LILRB6 or * LILRB7 or LILRA5

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  • Los Receptores leucocitarios tipo inmunoglobulina (LILR) también conocidos como ILTs, LIRs y CD85, son una familia de receptores que se encuentran situados en la superficie exterior de varios tipos de células, incluyendo linfocitos T, células NK, monocitos, macrófagos, células dendríticas y algunos de ellos en linfocitos B y granulocitos. Poseen funciones activadoras e inhibitoriasen. Se encuentran codificados por 13 genes localizados en el cromosoma 19q13.4​ (es)
  • The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains.They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. The human genes encoding these receptors are found in a gene cluster at chromosomal region 19q13.4. They include * LILRA1 * LILRA2 * LILRA3 * LILRA4 * LILRA5 * * LILRB1 * LILRB2 * LILRB3 * LILRB4 * LILRB5 * LILRB6 or * LILRB7 or LILRA5 A subset of LILR recognise MHC class I (also known as HLA class I in humans). The LILR family is a cluster of paired receptors with both activating and inhibitory functions. Of these, the inhibitory receptors LILRB1 and LILRB2 show a broad specificity for classical and non-classical MHC alleles with preferential binding to b2m-associated complexes. In contrast, the activating receptors LILRA1 and LILRA3 prefer b2m-independent free heavy chains of MHC class I, and in particular HLA-C alleles. (en)
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  • LILR
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  • 29859320 (xsd:integer)
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  • 3238 (xsd:nonNegativeInteger)
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  • 1030791233 (xsd:integer)
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  • 17 (xsd:integer)
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  • Leukocyte immunoglobulin-like receptors (en)
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  • LILR (en)
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  • Los Receptores leucocitarios tipo inmunoglobulina (LILR) también conocidos como ILTs, LIRs y CD85, son una familia de receptores que se encuentran situados en la superficie exterior de varios tipos de células, incluyendo linfocitos T, células NK, monocitos, macrófagos, células dendríticas y algunos de ellos en linfocitos B y granulocitos. Poseen funciones activadoras e inhibitoriasen. Se encuentran codificados por 13 genes localizados en el cromosoma 19q13.4​ (es)
  • The leukocyte immunoglobulin-like receptors (LILR) are a family of receptors possessing extracellular immunoglobulin domains.They are also known as CD85, ILTs and LIR, and can exert immunomodulatory effects on a wide range of immune cells. The human genes encoding these receptors are found in a gene cluster at chromosomal region 19q13.4. They include * LILRA1 * LILRA2 * LILRA3 * LILRA4 * LILRA5 * * LILRB1 * LILRB2 * LILRB3 * LILRB4 * LILRB5 * LILRB6 or * LILRB7 or LILRA5 (en)
rdfs:label
  • Receptores leucocitarios tipo inmunoglobulina (LILR) (es)
  • Leukocyte immunoglobulin-like receptors (en)
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