About: Jacalin

Property	Value
dbo:abstract	Jacalin is a plant-based lectin, but not a legume lectin, found in jackfruit. It has been studied for capturing O-glycoproteins such as mucins and IgA1, for potential applications in human immunology. Jacalin belongs to a family of galactose-binding lectins containing the Jacalin-like lectin domain and it has a tetrameric two-chain structure with a weight of 66 kDa Jacalin is preferably used in applications to isolate IgA from human serum, isolating human plasma glycoproteins and for applications in histochemistry. The lectin is blood group non-specific after neuraminidase treatment and agglutinates human erythrocytes at a concentration of ≥ 7,8 µg/ml. A post-translational proteolytic modification of Jacalin gives the lectin a novel carbohydrate-binding site involving the N-terminus of the a-chain. The relative affinities of the lectin for galactose derivatives, as well as the structural basis of its T-antigen specificity, are explained by its protein structure (en)
dbo:thumbnail	wiki-commons:Special:FilePath/PDB_1tp8_EBI.jpg?width=300
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dbo:wikiPageLength	1848 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1073048934 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Legume_lectin dbr:Lectin dbc:Plant_lectins dbr:Glycoprotein dbr:Jacalin-like_lectin_domain dbr:Jackfruit dbr:Immunology dbr:IgA dbr:Common_Bean dbr:Mucins dbr:N-terminus dbr:File:PDB_1tp8_EBI.jpg
dbp:wikiPageUsesTemplate	dbt:Reflist
dcterms:subject	dbc:Plant_lectins
gold:hypernym	dbr:Plant
rdf:type	yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:ConjugatedProtein114731135 yago:Glycoprotein114888310 yago:Lectin114889074 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Plant yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatPlantLectins
rdfs:comment	Jacalin is a plant-based lectin, but not a legume lectin, found in jackfruit. It has been studied for capturing O-glycoproteins such as mucins and IgA1, for potential applications in human immunology. Jacalin belongs to a family of galactose-binding lectins containing the Jacalin-like lectin domain and it has a tetrameric two-chain structure with a weight of 66 kDa (en)
rdfs:label	Jacalin (en)
owl:sameAs	freebase:Jacalin yago-res:Jacalin wikidata:Jacalin https://global.dbpedia.org/id/4oHr6
prov:wasDerivedFrom	wikipedia-en:Jacalin?oldid=1073048934&ns=0
foaf:depiction	wiki-commons:Special:FilePath/PDB_1tp8_EBI.jpg
foaf:isPrimaryTopicOf	wikipedia-en:Jacalin
is dbo:wikiPageWikiLink of	dbr:Lectin dbr:BanLec dbr:Jacalin-like_lectin_domain dbr:Avadhesha_Surolia
is foaf:primaryTopic of	wikipedia-en:Jacalin