About: Irazepine

Property	Value
dbo:abstract	Irazepine (Ro 7-1986/1) is a benzodiazepine derivative containing isothiocyanate functional group. It is a non-competitive benzodiazepine binding site antagonist. Irazepine and other alkylating benzodiazepines, such as , bind to brain benzodiazepine receptors in a non-competitive (covalent) fashion in vitro, and may exert a long-lasting anticonvulsant effect. (en) L'irazepina è uno psicofarmaco appartenente alla categoria delle benzodiazepine contenente il gruppo funzionale isotiocianato. L'irazepina e altre benzodiazepine alchilanti come la kenazepina, si legano ai recettori delle benzodiazepine cerebrali in modo non competitivo (covalente) in vitro e possono esercitare un effetto anticonvulsivante di lunga durata. (it)
dbo:casNumber	71735-92-7
dbo:fdaUniiCode	8ESB4CKN8K
dbo:pubchem	194406
dbo:thumbnail	wiki-commons:Special:FilePath/Irazepine.svg?width=300
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dbo:wikiPageWikiLink	dbr:Benzodiazepine dbr:Anticonvulsant dbr:Hoffmann-La_Roche dbc:Chloroarenes dbc:Fluoroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Isothiocyanates dbc:Lactams dbr:GABAA_receptor dbr:Isothiocyanate dbc:Anticonvulsants dbc:Benzodiazepines dbr:Kenazepine
dbp:c	18 (xsd:integer)
dbp:casNumber	71735 (xsd:integer)
dbp:chemspiderid	168688 (xsd:integer)
dbp:cl	1 (xsd:integer)
dbp:f	1 (xsd:integer)
dbp:h	13 (xsd:integer)
dbp:iupacName	7 (xsd:integer)
dbp:n	3 (xsd:integer)
dbp:o	1 (xsd:integer)
dbp:pubchem	194406 (xsd:integer)
dbp:s	1 (xsd:integer)
dbp:smiles	C1CNCCN=C=S (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	LTKSVYFAUMFQML-UHFFFAOYSA-N (en)
dbp:unii	8 (xsd:integer)
dbp:verifiedfields	changed (en)
dbp:watchedfields	changed (en)
dbp:width	170 (xsd:integer)
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dcterms:subject	dbc:Chloroarenes dbc:Fluoroarenes dbc:GABAA_receptor_positive_allosteric_modulators dbc:Isothiocyanates dbc:Lactams dbc:Anticonvulsants dbc:Benzodiazepines
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	Irazepine (Ro 7-1986/1) is a benzodiazepine derivative containing isothiocyanate functional group. It is a non-competitive benzodiazepine binding site antagonist. Irazepine and other alkylating benzodiazepines, such as , bind to brain benzodiazepine receptors in a non-competitive (covalent) fashion in vitro, and may exert a long-lasting anticonvulsant effect. (en) L'irazepina è uno psicofarmaco appartenente alla categoria delle benzodiazepine contenente il gruppo funzionale isotiocianato. L'irazepina e altre benzodiazepine alchilanti come la kenazepina, si legano ai recettori delle benzodiazepine cerebrali in modo non competitivo (covalente) in vitro e possono esercitare un effetto anticonvulsivante di lunga durata. (it)
rdfs:label	Irazepina (it) Irazepine (en)
owl:sameAs	yago-res:Irazepine wikidata:Irazepine dbpedia-it:Irazepine dbpedia-sr:Irazepine dbpedia-vi:Irazepine https://global.dbpedia.org/id/2MnwQ
prov:wasDerivedFrom	wikipedia-en:Irazepine?oldid=1107961067&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Irazepine.svg
foaf:isPrimaryTopicOf	wikipedia-en:Irazepine
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is foaf:primaryTopic of	wikipedia-en:Irazepine