About: Innexin

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Innexins are transmembrane proteins that form gap junctions in invertebrates. Gap junctions are composed of membrane proteins that form a channel permeable to ions and small molecules connecting the cytoplasm of adjacent cells. Although gap junctions provide similar functions in all multicellular organisms, it was not known what proteins invertebrates used for this purpose until the late 1990s. While the connexin family of gap junction proteins was well-characterized in vertebrates, no homologues were found in non-chordates.

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dbo:abstract
  • Innexins are transmembrane proteins that form gap junctions in invertebrates. Gap junctions are composed of membrane proteins that form a channel permeable to ions and small molecules connecting the cytoplasm of adjacent cells. Although gap junctions provide similar functions in all multicellular organisms, it was not known what proteins invertebrates used for this purpose until the late 1990s. While the connexin family of gap junction proteins was well-characterized in vertebrates, no homologues were found in non-chordates. Innexins or related proteins are widespread among Eumetazoa, with the exception of echinoderms. (en)
  • Le innexine sono proteine transmembrana che formano le gap junctions negli invertebrati. Le gap junctions sono formate da proteine di membrana che formano un canale permeabile agli ioni e a piccole molecole, connettendo funzionalmente il citoplasma di cellule adiacenti. Fino alla seconda metà degli anni 1990 non si conosceva quale proteina venisse usata come gap-junction negli invertebrati, sebbene in tutti gli organismi pluricellulari le gap junctions svolgessero una funzione simile. Mentre venne ben caratterizzata la famiglia delle gap-junctions nei vertebrati (connexine o connessine), nessun omologo fu ancora trovato nei non-cordati. (it)
  • 在多细胞生物中,相邻细胞膜上的半通道对接形成的缝隙连接,是细胞之间的连接方式之一,属于膜通道结构,参与介导相邻细胞间的信号传递。 * 在脊椎动物中,构成半通道的是连接子蛋白(或称“间隙连接蛋白”;)和(); * 在无脊椎动物中,形成半通道的间隙连接蛋白被命名为无脊椎连接蛋白(系的同源物;)。 蛋白普遍存在于真后生动物(除棘皮动物外)。 (zh)
dbo:symbol
  • Innexin
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 7364669 (xsd:integer)
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  • 11321 (xsd:nonNegativeInteger)
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  • 1118575149 (xsd:integer)
dbo:wikiPageWikiLink
dbp:bot
  • InternetArchiveBot (en)
dbp:date
  • November 2017 (en)
dbp:fixAttempted
  • yes (en)
dbp:interpro
  • IPR000990 (en)
dbp:name
  • Innexin (en)
dbp:opmFamily
  • 194 (xsd:integer)
dbp:opmProtein
  • 5 (xsd:integer)
dbp:pfam
  • PF00876 (en)
dbp:revision
  • 699838558 (xsd:integer)
dbp:sourcepath
  • http://tcdb.org/search/result.php?tc=1.a.25|sourcearticle= 1.A.25 The Gap Junction-forming Innexin Family (en)
dbp:symbol
  • Innexin (en)
dbp:tcdb
  • 1 (xsd:integer)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • 在多细胞生物中,相邻细胞膜上的半通道对接形成的缝隙连接,是细胞之间的连接方式之一,属于膜通道结构,参与介导相邻细胞间的信号传递。 * 在脊椎动物中,构成半通道的是连接子蛋白(或称“间隙连接蛋白”;)和(); * 在无脊椎动物中,形成半通道的间隙连接蛋白被命名为无脊椎连接蛋白(系的同源物;)。 蛋白普遍存在于真后生动物(除棘皮动物外)。 (zh)
  • Innexins are transmembrane proteins that form gap junctions in invertebrates. Gap junctions are composed of membrane proteins that form a channel permeable to ions and small molecules connecting the cytoplasm of adjacent cells. Although gap junctions provide similar functions in all multicellular organisms, it was not known what proteins invertebrates used for this purpose until the late 1990s. While the connexin family of gap junction proteins was well-characterized in vertebrates, no homologues were found in non-chordates. (en)
  • Le innexine sono proteine transmembrana che formano le gap junctions negli invertebrati. Le gap junctions sono formate da proteine di membrana che formano un canale permeabile agli ioni e a piccole molecole, connettendo funzionalmente il citoplasma di cellule adiacenti. (it)
rdfs:label
  • Innexin (en)
  • Innexina (it)
  • 无脊椎连接蛋白 (zh)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
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