About: Hsien Wu

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Hsien Wu (simplified Chinese: 吴宪; traditional Chinese: 吳憲; pinyin: Wú Xiàn; 24 November 1893 – 8 August 1959) was a Chinese biochemist and geneticist. He was the first to propose that protein denaturation was a purely conformational change, i.e., corresponded to protein unfolding and not to some chemical alteration of the protein. This crucial idea was popularized later by Linus Pauling and Alfred Mirsky. Wu left China in 1947 to reside in the United States; his wife and children joined him in 1949.

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  • Wu Hsien (* 24. November 1893 in Fuzhou; † 8. August 1959 in Boston) war ein chinesischer Biochemiker und Ernährungswissenschaftler. (de)
  • Hsien Wu (simplified Chinese: 吴宪; traditional Chinese: 吳憲; pinyin: Wú Xiàn; 24 November 1893 – 8 August 1959) was a Chinese biochemist and geneticist. He was the first to propose that protein denaturation was a purely conformational change, i.e., corresponded to protein unfolding and not to some chemical alteration of the protein. This crucial idea was popularized later by Linus Pauling and Alfred Mirsky. Wu was born in Fuzhou, Fujian, China. He studied at the Massachusetts Institute of Technology (undergraduate), and then trained at Harvard University (graduate) under Otto Folin, developing the first small-volume (≥ 0.1-mL sample) assay for blood sugar (Folin-Wu method). Wu then returned to China to a position at Peking Union Medical College, becoming head of the biochemistry department in 1924. At the end of that year, he married his research assistant Daisy Yen and would continue collaborating with her until his death in 1959. Wu left China in 1947 to reside in the United States; his wife and children joined him in 1949. Wu's son, Ray J. Wu, became the Liberty Hyde Bailey Professor of Molecular Genetics and Biology at Cornell University, and was active in studying transgenic plants, particularly rice. (en)
  • 吴宪(1893年11月24日-1959年8月8日),字陶民,男,福州侯官人,中国生物化学、营养学等领域研究的先驱,中央研究院院士。1931年于《中国生理学杂志》上最早提出了构形变化导致蛋白质变性的机理。在临床化学、气体与电解质的平衡、蛋白质化学、免疫化学、营养学以及氨基酸代谢等领域的研究居当时国际前沿地位,并为中国近代生物化学事业的建立和发展做出了开拓和奠基的工作。 (zh)
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  • 1893-11-24 (xsd:date)
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  • 1959-08-08 (xsd:date)
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dbp:almaMater
dbp:birthDate
  • 1893-11-24 (xsd:date)
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  • Fuzhou, Fujian, China (en)
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  • 1959-08-08 (xsd:date)
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  • Boston, Massachusetts, United States (en)
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  • Biochemistry (en)
  • Protein science (en)
dbp:name
  • Wu Hsien (en)
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  • China and United States of America (en)
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  • Wú Xiàn (en)
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  • 吴宪 (en)
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  • 吳憲 (en)
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  • Wu Hsien (* 24. November 1893 in Fuzhou; † 8. August 1959 in Boston) war ein chinesischer Biochemiker und Ernährungswissenschaftler. (de)
  • 吴宪(1893年11月24日-1959年8月8日),字陶民,男,福州侯官人,中国生物化学、营养学等领域研究的先驱,中央研究院院士。1931年于《中国生理学杂志》上最早提出了构形变化导致蛋白质变性的机理。在临床化学、气体与电解质的平衡、蛋白质化学、免疫化学、营养学以及氨基酸代谢等领域的研究居当时国际前沿地位,并为中国近代生物化学事业的建立和发展做出了开拓和奠基的工作。 (zh)
  • Hsien Wu (simplified Chinese: 吴宪; traditional Chinese: 吳憲; pinyin: Wú Xiàn; 24 November 1893 – 8 August 1959) was a Chinese biochemist and geneticist. He was the first to propose that protein denaturation was a purely conformational change, i.e., corresponded to protein unfolding and not to some chemical alteration of the protein. This crucial idea was popularized later by Linus Pauling and Alfred Mirsky. Wu left China in 1947 to reside in the United States; his wife and children joined him in 1949. (en)
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  • Wu Hsien (de)
  • Hsien Wu (en)
  • 吴宪 (zh)
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  • Wu Hsien (en)
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