Gypsyamber D'Souza is an American epidemiologist. She is a professor of epidemiology at the Johns Hopkins Bloomberg School of Public Health. D'Souza researches infectious diseases (including HPV, HIV, and SARS-CoV-2), cancer prevention, and translational epidemiology. She is a principal investigator of the Multicenter AIDS Cohort Study / Women's Interagency HIV Study Combined Cohort Study (Mwccs.org).