4-dimethylallyltryptophan N-methyltransferase (EC 2.1.1.261, fgaMT (gene), easF (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:4-(3-methylbut-2-enyl)-L-tryptophan N-methyltransferase. This enzyme catalyses the following chemical reaction S-adenosyl-L-methionine + 4-dimethylallyl-L-tryptophan S-adenosyl-L-homocysteine + 4-dimethylallyl-L-abrine The enzyme catalyses a step in the pathway leading to biosynthesis of ergot alkaloids in certain fungi.
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