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- In enzymology, a diiodophenylpyruvate reductase (EC 1.1.1.96) is an enzyme that catalyzes the chemical reaction 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductase. Other names in common use include aromatic alpha-keto acid, KAR, and 2-oxo acid reductase. (en)
- ジヨードフェニルピルビン酸デヒドロゲナーゼ（diiodophenylpyruvate reductase）は、次の化学反応を触媒する酸化還元酵素である。 すなわち、この酵素の基質はとNAD+、生成物はとNADHとH+である。 組織名は3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductaseで、別名にaromatic α-keto acid, KAR, 2-oxo acid reductaseがある。 (ja)
- La diiodofenilpiruvato reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 3-(3,5-diiodo-4-idrossifenil)lattato + NAD+ ⇄ 3-(3,5-diiodo-4-idrossifenil)piruvato + NADH + H+ I substrati sono caratterizzati da un anello aromatico con un piruvato come catena laterale. I substrati che presentano maggiore affinità sono derivati alogenati. I composti che contengono gruppi ossidrile o amminici in posizione 3 o 5 sono inattivi. (it)
- 二碘苯丙酮酸还原酶（英語：diiodophenylpyruvate reductase，EC 1.1.1.96（页面存档备份，存于互联网档案馆）），是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应： 3-(3,5-二碘-4-羟苯基)乳酸 + NAD+ 3-(3,5-二碘-4-羟苯基)丙酮酸 + NADH + H+ 二碘苯丙酮酸还原酶分子等电点为5.4，由两个相同的蛋白质亚基组成（亚基相对分子质量约为40,000D），人类二碘苯丙酮酸还原酶亚基由12号染色体上的基因编码，可能与乳酸脱氢酶B有近缘关系。这种酶的底物还可以是其他含有以丙酮酸支链作为取代基的芳环，其中卤代类衍生物作为底物具有较高活性。底物的活性从大到小按顺序排列为：草酰乙酸、3,5-二碘-4-羟苯基丙酮酸、、苯丙酮酸，而乙醛酸、丙酮酸、羟基丙酮酸以及在芳环3位或5位上有羟基或氨基的底物则仅具有极低活性或不具活性。 (zh)
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- diiodophenylpyruvate reductase (en)
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| rdfs:comment
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- ジヨードフェニルピルビン酸デヒドロゲナーゼ（diiodophenylpyruvate reductase）は、次の化学反応を触媒する酸化還元酵素である。 すなわち、この酵素の基質はとNAD+、生成物はとNADHとH+である。 組織名は3-(3,5-diiodo-4-hydroxyphenyl)lactate:NAD+ oxidoreductaseで、別名にaromatic α-keto acid, KAR, 2-oxo acid reductaseがある。 (ja)
- La diiodofenilpiruvato reduttasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 3-(3,5-diiodo-4-idrossifenil)lattato + NAD+ ⇄ 3-(3,5-diiodo-4-idrossifenil)piruvato + NADH + H+ I substrati sono caratterizzati da un anello aromatico con un piruvato come catena laterale. I substrati che presentano maggiore affinità sono derivati alogenati. I composti che contengono gruppi ossidrile o amminici in posizione 3 o 5 sono inattivi. (it)
- 二碘苯丙酮酸还原酶（英語：diiodophenylpyruvate reductase，EC 1.1.1.96（页面存档备份，存于互联网档案馆）），是一种以NAD+或NADP+为受体、作用于供体CH-OH基团上的氧化还原酶。这种酶能催化以下酶促反应： 3-(3,5-二碘-4-羟苯基)乳酸 + NAD+ 3-(3,5-二碘-4-羟苯基)丙酮酸 + NADH + H+ 二碘苯丙酮酸还原酶分子等电点为5.4，由两个相同的蛋白质亚基组成（亚基相对分子质量约为40,000D），人类二碘苯丙酮酸还原酶亚基由12号染色体上的基因编码，可能与乳酸脱氢酶B有近缘关系。这种酶的底物还可以是其他含有以丙酮酸支链作为取代基的芳环，其中卤代类衍生物作为底物具有较高活性。底物的活性从大到小按顺序排列为：草酰乙酸、3,5-二碘-4-羟苯基丙酮酸、、苯丙酮酸，而乙醛酸、丙酮酸、羟基丙酮酸以及在芳环3位或5位上有羟基或氨基的底物则仅具有极低活性或不具活性。 (zh)
- In enzymology, a diiodophenylpyruvate reductase (EC 1.1.1.96) is an enzyme that catalyzes the chemical reaction 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD+ 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + NADH + H+ Thus, the two substrates of this enzyme are and NAD+, whereas its 3 products are , NADH, and H+. (en)
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| rdfs:label
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- Diiodophenylpyruvate reductase (en)
- Diiodofenilpiruvato reduttasi (it)
- ジヨードフェニルピルビン酸デヒドロゲナーゼ (ja)
- 二碘苯丙酮酸还原酶 (zh)
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- diiodophenylpyruvate reductase (en)
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