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The Diego antigen (or blood group) system is composed of 21 blood factors or antigens carried on the Band 3 glycoprotein, also known as Anion Exchanger 1 (AE1). The antigens are inherited through various alleles of the gene SLC4A1 (Solute carrier family 4), located on human chromosome 17. The AE1 glycoprotein is expressed only in red blood cells and, in a shortened form, in some cells in the kidney. The Diegoa antigen is fairly common in Indigenous peoples of the Americas (in both North and South America) and East Asians, but very rare or absent in most other populations, supporting the theory that the two groups share common ancestry.

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  • The Diego antigen (or blood group) system is composed of 21 blood factors or antigens carried on the Band 3 glycoprotein, also known as Anion Exchanger 1 (AE1). The antigens are inherited through various alleles of the gene SLC4A1 (Solute carrier family 4), located on human chromosome 17. The AE1 glycoprotein is expressed only in red blood cells and, in a shortened form, in some cells in the kidney. The Diegoa antigen is fairly common in Indigenous peoples of the Americas (in both North and South America) and East Asians, but very rare or absent in most other populations, supporting the theory that the two groups share common ancestry. (en)
  • Le système Diégo est un système de groupe sanguin. (fr)
  • Il sistema Diego è uno dei 38 gruppi sanguigni umani, ed è composto da 21 antigeni espressi sulla glicoproteina di banda 3, nota anche come Anion exchanger 1 (AE1); gli antigeni sono ereditati da vari alleli del gene SLC4A1 (Solute carrier family 4 member 1), situato sul cromosoma 17. La glicoproteina AE1 è espressa solo sui globuli rossi e, in forma ridotta, in alcune cellule del rene. (it)
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  • The Diego antigen (or blood group) system is composed of 21 blood factors or antigens carried on the Band 3 glycoprotein, also known as Anion Exchanger 1 (AE1). The antigens are inherited through various alleles of the gene SLC4A1 (Solute carrier family 4), located on human chromosome 17. The AE1 glycoprotein is expressed only in red blood cells and, in a shortened form, in some cells in the kidney. The Diegoa antigen is fairly common in Indigenous peoples of the Americas (in both North and South America) and East Asians, but very rare or absent in most other populations, supporting the theory that the two groups share common ancestry. (en)
  • Le système Diégo est un système de groupe sanguin. (fr)
  • Il sistema Diego è uno dei 38 gruppi sanguigni umani, ed è composto da 21 antigeni espressi sulla glicoproteina di banda 3, nota anche come Anion exchanger 1 (AE1); gli antigeni sono ereditati da vari alleli del gene SLC4A1 (Solute carrier family 4 member 1), situato sul cromosoma 17. La glicoproteina AE1 è espressa solo sui globuli rossi e, in forma ridotta, in alcune cellule del rene. (it)
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  • Diego antigen system (en)
  • Sistema Diego (it)
  • Système Diégo (fr)
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