About: Dextrallorphan

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Dextrallorphan (DXA) is an chemical of the morphinan class that is used in scientific research. It acts as a σ1 receptor agonist and NMDA receptor antagonist. It has no significant affinity for the σ2, μ-opioid, or δ-opioid receptor, or for the serotonin or norepinephrine transporter.As an NMDA receptor antagonist, in vivo, it is approximately twice as potent as dextromethorphan, and five-fold less potent than dextrorphan.

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  • Dextrallorphan (DXA) is an chemical of the morphinan class that is used in scientific research. It acts as a σ1 receptor agonist and NMDA receptor antagonist. It has no significant affinity for the σ2, μ-opioid, or δ-opioid receptor, or for the serotonin or norepinephrine transporter.As an NMDA receptor antagonist, in vivo, it is approximately twice as potent as dextromethorphan, and five-fold less potent than dextrorphan. (en)
dbo:casNumber
  • 5822-43-5
dbo:pubchem
  • 5748237
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  • 26975585 (xsd:integer)
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  • 9878 (xsd:nonNegativeInteger)
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  • 1092792254 (xsd:integer)
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dbp:atcPrefix
  • none (en)
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  • 19 (xsd:integer)
dbp:casNumber
  • 5822 (xsd:integer)
dbp:chemspiderid
  • 2339009 (xsd:integer)
dbp:h
  • 25 (xsd:integer)
dbp:iupacName
  • --17-allylmorphinan-3-ol (en)
dbp:legalStatus
  • Uncontrolled (en)
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  • 1 (xsd:integer)
dbp:o
  • 1 (xsd:integer)
dbp:pubchem
  • 5748237 (xsd:integer)
dbp:routesOfAdministration
  • Oral (en)
dbp:smiles
  • Oc1ccc3c[C@]24[C@@H]CCCC4 (en)
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rdfs:comment
  • Dextrallorphan (DXA) is an chemical of the morphinan class that is used in scientific research. It acts as a σ1 receptor agonist and NMDA receptor antagonist. It has no significant affinity for the σ2, μ-opioid, or δ-opioid receptor, or for the serotonin or norepinephrine transporter.As an NMDA receptor antagonist, in vivo, it is approximately twice as potent as dextromethorphan, and five-fold less potent than dextrorphan. (en)
rdfs:label
  • Dextrallorphan (en)
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