About: Devimistat

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Devimistat (INN; development code CPI-613) is an experimental drug being developed by Rafael Pharmaceuticals. It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML).

Property Value
dbo:abstract
  • Devimistat (INN; development code CPI-613) is an experimental drug being developed by Rafael Pharmaceuticals. It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML). Devimistat's mechanism of action differs from other drugs, operating on the tricarboxylic acid cycle and inhibiting enzymes involved with cancer cell energy metabolism. A lipoic acid derivative different from standard cytotoxic chemotherapy, devimistat is currently being studied in combination with modified FOLFIRINOX to treat various solid tumors and heme malignancies. (en)
dbo:casNumber
  • 95809-78-2
dbo:chEMBL
  • 3186849
dbo:drugbank
  • 12109
dbo:fdaUniiCode
  • E76113IR49
dbo:pubchem
  • 24770514
dbo:thumbnail
dbo:wikiPageID
  • 62034187 (xsd:integer)
dbo:wikiPageLength
  • 4157 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1030997838 (xsd:integer)
dbo:wikiPageWikiLink
dbp:c
  • 22 (xsd:integer)
dbp:casNumber
  • 95809 (xsd:integer)
dbp:chembl
  • 3186849 (xsd:integer)
dbp:chemspiderid
  • 28189062 (xsd:integer)
dbp:drugbank
  • 12109 (xsd:integer)
dbp:h
  • 28 (xsd:integer)
dbp:iupacName
  • 68 (xsd:integer)
dbp:legalStatus
  • Investigational (en)
dbp:o
  • 2 (xsd:integer)
dbp:pubchem
  • 24770514 (xsd:integer)
dbp:s
  • 2 (xsd:integer)
dbp:smiles
  • C1=CC=CCSCCCSCC2=CC=CC=C2 (en)
dbp:stdinchi
  • 1 (xsd:integer)
dbp:stdinchikey
  • ZYRLHJIMTROTBO-UHFFFAOYSA-N (en)
dbp:synonyms
  • CPI-613 (en)
dbp:unii
  • E76113IR49 (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Devimistat (INN; development code CPI-613) is an experimental drug being developed by Rafael Pharmaceuticals. It is being studied for the treatment of patients with metastatic pancreatic cancer and relapsed or refractory acute myeloid leukemia (AML). (en)
rdfs:label
  • Devimistat (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License