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- DXP reductoisomerase (1-deoxy-D-xylulose 5-phosphate reductoisomerase or DXR) is an enzyme that interconverts 1-deoxy-D-xylulose 5-phosphate (DXP) and 2-C-methyl-D-erythritol 4-phosphate (MEP).
* 1-Deoxy-D-xylulose 5-phosphate
* 2-C-methyl-D-erythritol 4-phosphate It is classified under EC 1.1.1.267. It is normally abbreviated DXR, but it is sometimes named IspC, as the product of the ispC gene. DXR is part of the MEP pathway (nonmevalonate pathway) of isoprenoid precursor biosynthesis. DXR is inhibited by fosmidomycin. This enzyme is required for terpenoid biosynthesis in some organisms, since it is a key enzyme on the MEP pathway for the production of the isoprenoid precursors IPP and DMAPP. In Arabidopsis thaliana 1-deoxy-D-xylulose 5-phosphate reductoisomerase is the first committed enzyme of the MEP pathway for isoprenoid precursor biosynthesis. The enzyme requires Mn2+, Co2+ or Mg2+ for activity, with Mn2+ being most effective. (en)
- La 1-désoxy-D-xylulose-5-phosphate réductoisomérase, ou DXP réductoisomérase, est une oxydoréductase qui catalyse la conversion du 1-désoxy-D-xylulose-5-phosphate en 2-C-méthylérythritol-4-phosphate : Des ions cobalt Co2+, manganèse Mn2+ ou magnésium Mg+ interviennent comme cofacteurs dans cette réaction. Cette enzyme intervient à la deuxième étape de la voie du méthylérythritol phosphate, qui est une voie métabolique de biosynthèse de l'isopentényl-pyrophosphate (IPP) et du diméthylallyl-pyrophosphate (DMAPP) alternative à la voie du mévalonate chez les plantes, certains protozoaires et la plupart des bactéries, l'IPP et le DMAPP étant des métabolites qui conduisent notamment à la synthèse des terpénoïdes.
* Portail de la biochimie (fr)
- La 1-deossi-D-xilulosio-5-fosfato reduttoisomerasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 2-C-metil-D-eritrolo 4-fosfato + NADP+ ⇄ 1-deossi-D-xilulosio 5-fosfato + NADPH + H+ (it)
- 1-デオキシ-D-キシルロース-5-リン酸レダクトイソメラーゼまたはDXPレダクトイソメラーゼ（1-deoxy-D-xylulose-5-phosphate reductoisomerase, DXP reductoisomerase）は、2-C-メチルエリトリトール-4-リン酸と1-デオキシ-D-キシルロース-5-リン酸とを相互変換する酸化還元酵素である。イソプレノイド生合成における非メバロン酸経路を構成する酵素の一つである。
* 2-C-メチルエリトリトール-4-リン酸
* 1-デオキシ-D-キシルロース-5-リン酸 組織名は2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase(isomerizing)で、別名にDXP-reductoisomerase, 1-deoxy-D-xylulose-5-phosphate isomeroreductase, 2-C-methyl-D-erythritol 4-phosphate (MEP) synthaseがある。 (ja)
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- crystal structure of DXR in complex with the substrate 1-deoxy-(D)-xylulose 5-phosphate (en)
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- DXP reductoisomerase (en)
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- La 1-deossi-D-xilulosio-5-fosfato reduttoisomerasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: 2-C-metil-D-eritrolo 4-fosfato + NADP+ ⇄ 1-deossi-D-xilulosio 5-fosfato + NADPH + H+ (it)
- 1-デオキシ-D-キシルロース-5-リン酸レダクトイソメラーゼまたはDXPレダクトイソメラーゼ（1-deoxy-D-xylulose-5-phosphate reductoisomerase, DXP reductoisomerase）は、2-C-メチルエリトリトール-4-リン酸と1-デオキシ-D-キシルロース-5-リン酸とを相互変換する酸化還元酵素である。イソプレノイド生合成における非メバロン酸経路を構成する酵素の一つである。
* 2-C-メチルエリトリトール-4-リン酸
* 1-デオキシ-D-キシルロース-5-リン酸 組織名は2-C-methyl-D-erythritol-4-phosphate:NADP+ oxidoreductase(isomerizing)で、別名にDXP-reductoisomerase, 1-deoxy-D-xylulose-5-phosphate isomeroreductase, 2-C-methyl-D-erythritol 4-phosphate (MEP) synthaseがある。 (ja)
- DXP reductoisomerase (1-deoxy-D-xylulose 5-phosphate reductoisomerase or DXR) is an enzyme that interconverts 1-deoxy-D-xylulose 5-phosphate (DXP) and 2-C-methyl-D-erythritol 4-phosphate (MEP).
* 1-Deoxy-D-xylulose 5-phosphate
* 2-C-methyl-D-erythritol 4-phosphate It is classified under EC 1.1.1.267. It is normally abbreviated DXR, but it is sometimes named IspC, as the product of the ispC gene. DXR is part of the MEP pathway (nonmevalonate pathway) of isoprenoid precursor biosynthesis. DXR is inhibited by fosmidomycin. (en)
- La 1-désoxy-D-xylulose-5-phosphate réductoisomérase, ou DXP réductoisomérase, est une oxydoréductase qui catalyse la conversion du 1-désoxy-D-xylulose-5-phosphate en 2-C-méthylérythritol-4-phosphate : Des ions cobalt Co2+, manganèse Mn2+ ou magnésium Mg+ interviennent comme cofacteurs dans cette réaction.
* Portail de la biochimie (fr)
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- DXP reductoisomerase (en)
- 1-Désoxy-D-xylulose-5-phosphate réductoisomérase (fr)
- 1-deossi-D-xilulosio-5-fosfato reduttoisomerasi (it)
- 1-デオキシ-D-キシルロース-5-リン酸レダクトイソメラーゼ (ja)
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