About: DEAD box

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DEAD box proteins are involved in an assortment of metabolic processes that typically involve RNAs, but in some cases also other nucleic acids. They are highly conserved in nine motifs and can be found in most prokaryotes and eukaryotes, but not all. Many organisms, including humans, contain DEAD-box (SF2) helicases, which are involved in RNA metabolism.

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  • DEAD box proteins are involved in an assortment of metabolic processes that typically involve RNAs, but in some cases also other nucleic acids. They are highly conserved in nine motifs and can be found in most prokaryotes and eukaryotes, but not all. Many organisms, including humans, contain DEAD-box (SF2) helicases, which are involved in RNA metabolism. (en)
  • DEAD box為一蛋白質家族的通稱，在原核生物與真核生物細胞中皆有，因其中一個結構域有一天門冬胺酸-麩胺酸-丙胺酸-天門冬胺酸（DEAD）的氨基酸序列而得名。此家族的蛋白多參與RNA相關反應，有許多蛋白為RNA解旋酶，可以消耗ATP的機制將雙股RNA解開。 DEAH家族與SKI2家族的蛋白序列也與DEAD box家族的蛋白相似，三者合稱DExD/H家族蛋白。 (zh)
dbo:symbol
  • DEAD
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dbo:wikiPageID
  • 14476027 (xsd:integer)
dbo:wikiPageLength
  • 12341 (xsd:nonNegativeInteger)
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  • 1081018404 (xsd:integer)
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dbp:caption
  • Structure of the amino terminal domain of yeast initiation factor 4A. PDB (en)
dbp:cdd
  • cd00046 (en)
  • cd00268 (en)
dbp:interpro
  • IPR011545 (en)
dbp:name
  • DEAD/DEAH box helicase (en)
dbp:pfam
  • PF00270 (en)
dbp:pfamClan
  • CL0023 (en)
dbp:prosite
  • PDOC00039 (en)
dbp:scop
  • 1 (xsd:integer)
dbp:symbol
  • DEAD (en)
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  • DEAD box proteins are involved in an assortment of metabolic processes that typically involve RNAs, but in some cases also other nucleic acids. They are highly conserved in nine motifs and can be found in most prokaryotes and eukaryotes, but not all. Many organisms, including humans, contain DEAD-box (SF2) helicases, which are involved in RNA metabolism. (en)
  • DEAD box為一蛋白質家族的通稱，在原核生物與真核生物細胞中皆有，因其中一個結構域有一天門冬胺酸-麩胺酸-丙胺酸-天門冬胺酸（DEAD）的氨基酸序列而得名。此家族的蛋白多參與RNA相關反應，有許多蛋白為RNA解旋酶，可以消耗ATP的機制將雙股RNA解開。 DEAH家族與SKI2家族的蛋白序列也與DEAD box家族的蛋白相似，三者合稱DExD/H家族蛋白。 (zh)
rdfs:label
  • DEAD box (en)
  • DEAD box (zh)
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