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In enzymology, a D-2-hydroxyglutarate dehydrogenase (EC 1.1.99.39) is an enzyme that catalyzes the chemical reaction (R)-2-hydroxyglutarate + acceptor 2-oxoglutarate + reduced acceptor Thus, the two substrates of this enzyme are (R)-2-hydroxyglutarate and acceptor, whereas its two products are 2-oxoglutarate and reduced acceptor. The enzyme activity has been confirmed in animals as well as in plants.
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