An Entity of Type: combination drug, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Chlorproguanil/dapsone/artesunate (abbreviated CDA) was an experimental antimalarial treatment that entered Phase III clinical trials in 2006. Development was halted because it was associated with an increased risk of haemolytic anaemia in patients with glucose-6-phosphate dehydrogenase deficiency. It consists of chlorproguanil, dapsone, and artesunate. (It can also be interpreted as Lapdap+artesunate.)

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  • Chlorproguanil/dapsone/artesunate (abbreviated CDA) was an experimental antimalarial treatment that entered Phase III clinical trials in 2006. Development was halted because it was associated with an increased risk of haemolytic anaemia in patients with glucose-6-phosphate dehydrogenase deficiency. It consists of chlorproguanil, dapsone, and artesunate. (It can also be interpreted as Lapdap+artesunate.) Studies compared this combination against artemether/lumefantrine (Coartem) and against chlorproguanil/dapsone (Lapdap). This drug was developed in collaboration between GlaxoSmithKline, UNICEF, the World Bank, Medicines for Malaria Venture and the WHO (WHO/TDR), the Liverpool School of Tropical Medicine, and the London School of Hygiene and Tropical Medicine. (en)
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  • none (en)
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dbp:component
  • Artesunate (en)
  • Chlorproguanil (en)
  • Dapsone (en)
dbp:legalStatus
  • Development halted (en)
dbp:type
  • combo (en)
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rdfs:comment
  • Chlorproguanil/dapsone/artesunate (abbreviated CDA) was an experimental antimalarial treatment that entered Phase III clinical trials in 2006. Development was halted because it was associated with an increased risk of haemolytic anaemia in patients with glucose-6-phosphate dehydrogenase deficiency. It consists of chlorproguanil, dapsone, and artesunate. (It can also be interpreted as Lapdap+artesunate.) (en)
rdfs:label
  • Chlorproguanil/dapsone/artesunate (en)
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