About: Bufuralol

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Bufuralol is a potent beta-adrenoceptor antagonist with partial agonist activity. It is metabolized by CYP2D6. Most beta blockers are aryloxypropanolamine-based. In this rare exception, the benzofuran oxygen is part of a ring instead of derived from the epichlorohydrin precursor.

Property	Value
dbo:abstract	Bufuralol is a potent beta-adrenoceptor antagonist with partial agonist activity. It is metabolized by CYP2D6. Most beta blockers are aryloxypropanolamine-based. In this rare exception, the benzofuran oxygen is part of a ring instead of derived from the epichlorohydrin precursor. (en) Bufuralol es un potente betabloqueador con actividad agonista parcial. Es metabolizado por CYP2D6. (es)
dbo:alternativeName	2-(tert-Butylamino)-1-(7-ethylbenzofuran-2-yl)ethan-1-ol (en) 2-(tert-Butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethanol (en)
dbo:iupacName	2-(tert-Butylamino)-1-(7-ethyl-1-benzofuran-2-yl)ethan-1-ol (en)
dbo:thumbnail	wiki-commons:Special:FilePath/Bufuralol.svg?width=300
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dbo:wikiPageLength	2221 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	911601789 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Partial_agonist dbr:Beta_blocker dbr:Epichlorohydrin dbc:Benzofuranethanamines dbc:Beta_blockers dbc:N-tert-butyl-phenoxypropanolamines dbr:CYP2D6 dbr:Beta-adrenoceptor_antagonist
dbp:imagefile	Bufuralol.svg (en)
dbp:imagesize	200 (xsd:integer)
dbp:othernames	2 (xsd:integer)
dbp:pin	2 (xsd:integer)
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dcterms:subject	dbc:Benzofuranethanamines dbc:Beta_blockers dbc:N-tert-butyl-phenoxypropanolamines
gold:hypernym	dbr:Antagonist
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 yago:WikicatBenzofurans yago:Abstraction100002137 yago:Benzofuran114898101 yago:Chemical114806838 yago:Compound114818238 yago:Material114580897 yago:Matter100020827 yago:Part113809207 yago:PhysicalEntity100001930 yago:Relation100031921 dbo:ChemicalCompound dbo:Drug yago:Substance100019613
rdfs:comment	Bufuralol is a potent beta-adrenoceptor antagonist with partial agonist activity. It is metabolized by CYP2D6. Most beta blockers are aryloxypropanolamine-based. In this rare exception, the benzofuran oxygen is part of a ring instead of derived from the epichlorohydrin precursor. (en) Bufuralol es un potente betabloqueador con actividad agonista parcial. Es metabolizado por CYP2D6. (es)
rdfs:label	Bufuralol (es) Bufuralol (en)
owl:sameAs	freebase:Bufuralol wikidata:Bufuralol dbpedia-es:Bufuralol dbpedia-fa:Bufuralol dbpedia-sh:Bufuralol dbpedia-sr:Bufuralol https://global.dbpedia.org/id/4d2qT yago-res:Bufuralol
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foaf:depiction	wiki-commons:Special:FilePath/Bufuralol.svg
foaf:isPrimaryTopicOf	wikipedia-en:Bufuralol
is dbo:wikiPageWikiLink of	dbr:List_of_adrenergic_drugs dbr:C16H23NO2 dbr:Cholesterol_24-hydroxylase dbr:CYP2D6 dbr:List_of_drugs:_Bs–Bz
is foaf:primaryTopic of	wikipedia-en:Bufuralol