About: Bromelain (pharmacology)

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Bromelain, a concentrate of proteolytic enzymes from the pineapple plant, is used in medicine. It is approved in the European Union for the debridement (removal of eschar, that is dead and damaged tissue) of severe burn wounds under the brand name NexoBrid. In the US, it has completed Phase III clinical trials and has the tentative trade name Debrase. It was developed by , Germany; and Teva is responsible for development and marketing in the US. The medicine has been granted orphan drug status by the European Medicines Agency (EMA).

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dbo:abstract
  • Bromelain, a concentrate of proteolytic enzymes from the pineapple plant, is used in medicine. It is approved in the European Union for the debridement (removal of eschar, that is dead and damaged tissue) of severe burn wounds under the brand name NexoBrid. In the US, it has completed Phase III clinical trials and has the tentative trade name Debrase. It was developed by , Germany; and Teva is responsible for development and marketing in the US. The medicine has been granted orphan drug status by the European Medicines Agency (EMA). In other contexts, bromelain has been researched for possible anti-inflammatory effects in treating a range of conditions or diseases, but results of these studies are mixed and regarded as preliminary. (en)
dbo:alternativeName
  • NexoBrid (en)
dbo:casNumber
  • 37189-34-7
dbo:fdaUniiCode
  • ZLM4P8929R
dbo:kegg
  • D03162
dbo:wikiPageExternalLink
dbo:wikiPageID
  • 46250827 (xsd:integer)
dbo:wikiPageLength
  • 6508 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1113122969 (xsd:integer)
dbo:wikiPageWikiLink
dbp:atcPrefix
  • D03 (en)
dbp:atcSuffix
  • BA03 (en)
dbp:bioavailability
  • Depends on wound surface and depth (en)
dbp:casNumber
  • 37189 (xsd:integer)
dbp:chemspiderid
  • none (en)
dbp:drugName
  • Concentrate of proteolytic enzymes enriched in bromelain (en)
dbp:eliminationHalfLife
  • 12600.0
dbp:kegg
  • D03162 (en)
dbp:legalEu
  • Rx-only (en)
dbp:legalStatus
  • Rx-only (en)
dbp:legalUk
  • POM (en)
dbp:proteinBound
  • ~50% (en)
dbp:routesOfAdministration
  • Locally onto the wound (en)
dbp:tradename
  • NexoBrid (en)
dbp:unii
  • ZLM4P8929R (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Bromelain, a concentrate of proteolytic enzymes from the pineapple plant, is used in medicine. It is approved in the European Union for the debridement (removal of eschar, that is dead and damaged tissue) of severe burn wounds under the brand name NexoBrid. In the US, it has completed Phase III clinical trials and has the tentative trade name Debrase. It was developed by , Germany; and Teva is responsible for development and marketing in the US. The medicine has been granted orphan drug status by the European Medicines Agency (EMA). (en)
rdfs:label
  • Bromelain (pharmacology) (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
foaf:name
  • Concentrate of proteolytic enzymes enriched in bromelain (en)
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is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
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