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In enzymology, a beta-adrenergic-receptor kinase (EC 2.7.11.15) is an enzyme that catalyzes the chemical reaction: ATP + [beta-adrenergic receptor] ADP + phospho-[beta-adrenergic receptor] Thus, the two substrates of this enzyme are ATP and beta-adrenergic receptor, whereas its two products are ADP and .

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dbo:abstract
  • In enzymology, a beta-adrenergic-receptor kinase (EC 2.7.11.15) is an enzyme that catalyzes the chemical reaction: ATP + [beta-adrenergic receptor] ADP + phospho-[beta-adrenergic receptor] Thus, the two substrates of this enzyme are ATP and beta-adrenergic receptor, whereas its two products are ADP and . This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[beta-adrenergic receptor] phosphotransferase. Other names in common use include ATP:beta-adrenergic-receptor phosphotransferase, [beta-adrenergic-receptor] kinase, beta-adrenergic receptor-specific kinase, beta-AR kinase, beta-ARK, beta-ARK 1, beta-ARK 2, beta-receptor kinase, GRK2, GRK3, beta-adrenergic-receptor kinase (phosphorylating), beta2ARK, betaARK1, beta-adrenoceptor kinase, beta-adrenoceptor kinase 1, beta-adrenoceptor kinase 2, ADRBK1, BARK1, adrenergic receptor kinase, and STK15. Several compounds are known to inhibit this enzyme, including Zinc, and Digitonin. (en)
dbo:ecNumber
  • 2.7.11.15
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  • 14676968 (xsd:integer)
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  • 3915 (xsd:nonNegativeInteger)
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  • 1025587360 (xsd:integer)
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dbp:casNumber
  • 102925 (xsd:integer)
dbp:ecNumber
  • 2.700000 (xsd:double)
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  • 47696 (xsd:integer)
dbp:iubmbEcNumber
  • 2 (xsd:integer)
dbp:name
  • beta-adrenergic receptor kinase (en)
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  • In enzymology, a beta-adrenergic-receptor kinase (EC 2.7.11.15) is an enzyme that catalyzes the chemical reaction: ATP + [beta-adrenergic receptor] ADP + phospho-[beta-adrenergic receptor] Thus, the two substrates of this enzyme are ATP and beta-adrenergic receptor, whereas its two products are ADP and . (en)
rdfs:label
  • Beta-adrenergic-receptor kinase (en)
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  • beta-adrenergic receptor kinase (en)
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