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Sphinganine C4-monooxygenase (EC 1.14.13.169, sphingolipid C4-hydroxylase, SUR2 (gene), SBH1 (gene), SBH2 (gene)) is an enzyme with systematic name sphinganine,NADPH:oxygen oxidoreductase (C4-hydroxylating). This enzyme catalyses the following chemical reaction sphinganine + NADPH + H+ + O2 phytosphingosine + NADP+ + H2O Sphinganine C4-monooxygenase is involved in the biosynthesis of sphingolipids in yeast and plants.
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