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Adoptive immunity acts in a host after their immunological components are withdrawn, their immunological activity is modified extracorporeally, and then reinfused into the same host. This process in its former part is analogous to adoption: a child is once adopted out from their home, grown up, and then returned to their home of birth. Transferred immunological components include immune cells such as T lymphocytes or tumour-infiltrating lymphocytes, NK cells, macrophages, or B cells. There seems to be some variation in usage of this term.

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  • Adoptive immunity acts in a host after their immunological components are withdrawn, their immunological activity is modified extracorporeally, and then reinfused into the same host. This process in its former part is analogous to adoption: a child is once adopted out from their home, grown up, and then returned to their home of birth. Transferred immunological components include immune cells such as T lymphocytes or tumour-infiltrating lymphocytes, NK cells, macrophages, or B cells. There seems to be some variation in usage of this term. 1. * Transferred components are immune cells and autologous as above. 2. * Transfer of immune cells is made between different individuals of monozygotic twins in human or of the same pure line in experimental animals from immunologically sensitized to naive host, where transferred cells are engrafted without rejection or GVHD in the new host. 3. * Transfer of cells are made between allogeneic hosts but the new host is irradiated for preventing rejection or GVHD. 4. * Transfer of cells are made between allogeneic hosts. 5. * Transferred components include cells as well as immune molecules such as immunoglobulins between allogeneic hosts. The term is used almost synonymously for "passive immunity" in some situations, however, passive immunity acts among xenogeneic hosts; for example, in snake venom immunotherapy, antivenom IgG is obtained from sensitized horse and inoculated to humans. (en)
  • 过继免疫(Adoptive immunity)狭义上,指的是将宿主免疫成分抽取出体外,经修饰其免疫活性后再输注回同一宿主,而此成分具有免疫性。转移的成分主要为免疫细胞,例如T淋巴细胞或肿瘤浸润淋巴细胞,自然杀手细胞,巨噬细胞或B细胞。因此,此术语一般指人为而具治疗性的被动免疫策略。 由于被动免疫在治疗上是指免疫在异种宿主上发生,例如蛇毒免疫疗法,因此过继免疫的意义有别于被动免疫。但广义上,过继免疫可涵盖另一种情况:采集已接触过某抗原而被免疫供者的致敏淋巴细胞,输注给另一个未接触过该抗原受者,使其被动获得相应的细胞免疫反应能力。 (zh)
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  • 过继免疫(Adoptive immunity)狭义上,指的是将宿主免疫成分抽取出体外,经修饰其免疫活性后再输注回同一宿主,而此成分具有免疫性。转移的成分主要为免疫细胞,例如T淋巴细胞或肿瘤浸润淋巴细胞,自然杀手细胞,巨噬细胞或B细胞。因此,此术语一般指人为而具治疗性的被动免疫策略。 由于被动免疫在治疗上是指免疫在异种宿主上发生,例如蛇毒免疫疗法,因此过继免疫的意义有别于被动免疫。但广义上,过继免疫可涵盖另一种情况:采集已接触过某抗原而被免疫供者的致敏淋巴细胞,输注给另一个未接触过该抗原受者,使其被动获得相应的细胞免疫反应能力。 (zh)
  • Adoptive immunity acts in a host after their immunological components are withdrawn, their immunological activity is modified extracorporeally, and then reinfused into the same host. This process in its former part is analogous to adoption: a child is once adopted out from their home, grown up, and then returned to their home of birth. Transferred immunological components include immune cells such as T lymphocytes or tumour-infiltrating lymphocytes, NK cells, macrophages, or B cells. There seems to be some variation in usage of this term. (en)
rdfs:label
  • Adoptive immunity (en)
  • 过继免疫 (zh)
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