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- 5-(Nonyloxy)tryptamine is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length in this series gives generally increasing potency and selectivity for 5-HT1B, with highest activity found for the nonyloxy derivative, having a 5-HT1B binding affinity of 1.0 nM, and around 300-fold selectivity over the related 5-HT1A receptor. (en)
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- 2617 (xsd:nonNegativeInteger)
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- CCCCCCCCCOC1=CC2=CNC=C2CCN (en)
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- YHSMSRREJYOGQJ-UHFFFAOYSA-N (en)
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| rdfs:comment
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- 5-(Nonyloxy)tryptamine is a tryptamine derivative which acts as a selective agonist at the 5-HT1B receptor. Increasing the O-alkoxy chain length in this series gives generally increasing potency and selectivity for 5-HT1B, with highest activity found for the nonyloxy derivative, having a 5-HT1B binding affinity of 1.0 nM, and around 300-fold selectivity over the related 5-HT1A receptor. (en)
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- 5-(Nonyloxy)tryptamine (en)
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